Oto-Neuro-Ophthalmology (ONO)

A special issue of Clinical and Translational Neuroscience (ISSN 2514-183X).

Deadline for manuscript submissions: closed (1 May 2022) | Viewed by 3464

Special Issue Editors


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Guest Editor
Department of Neurology, Zurich University Hospital, Zurich, Switzerland
Interests: neurology; vertigo; dizziness; balance disorders; eye movement disorders; treatment; vestibulo-ocular reflex; concussion; inner ear disease; cerebellar

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Guest Editor
Department of Neurology, Seoul National University, Seoul, Republic of Korea
Interests: neurology; vertigo; dizziness; balance disorders; eye movement disorders; treatment; vestibulo-ocular reflex; concussion; inner ear disease; cerebellar

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Guest Editor
Neurology, Cantonal Hospital of Baden, Baden, Switzerland
Interests: neurology; vertigo; dizziness; balance disorders; eye movement disorders; treatment; vestibulo-ocular reflex; concussion; inner ear disease; cerebellar

Special Issue Information

Dear Colleagues,

Neuro-otology and neuro-ophthalmology are clinical fields destined to be highly interdisciplinary and integrative in order to offer state-of-the-art diagnosis and treatment to patients with vertigo, dizziness, imbalance, eye movement disorders, and disorders of the afferent visual pathways. Specialists, frontline primary care givers, and emergency-department physicians involved in the assessment of otorhinolaryngology, neurology, and ophthalmology (ONO, oto-neuro-ophthalmology) patients are confronted with a broad differential diagnosis including dangerous, life-threatening disorders and difficult decisions regarding which tests to order and to select evidence-based treatments. With dizziness and vertigo being amongst the most frequent causes for primary care physician and ED visits, a profound understanding of underlying pathomechanisms, diagnostic algorithms, and treatment options is essential. This Special Issue focuses on these topics among otorhinolaryngology, neurology, and ophthalmology. It will include studies from basic, translational, and clinical research, including single case reports, case series, lessons learned from diagnostic errors, and focused reviews. Thus, this Special Issue aims to extend the current knowledge in this extremely dynamic field, using a highly integrative approach across many subspecialities and facets centered on the dizzy patient.

Prof. Dr. Dominik Straumann
Prof. Dr. Ji-Soo Kim
Dr. Alexander Tarnutzer
Guest Editors

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Keywords

  • vertigo
  • dizziness
  • vestibular
  • balance
  • cerebellum
  • eye movements
  • vestibulo-ocular reflex
  • nystagmus
  • gaze-palsy
  • diplopia
  • oscillopsia
  • semicircular canals
  • otolith organs
  • hearing

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Published Papers (1 paper)

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Research

12 pages, 2517 KiB  
Article
Rapid Automatized Picture Naming in an Outpatient Concussion Center: Quantitative Eye Movements during the Mobile Universal Lexicon Evaluation System (MULES) Test
by Todd E. Hudson, Jenna Conway, John-Ross Rizzo, John Martone, Liyung T. Chou, Laura J. Balcer, Steven L. Galetta and Janet C. Rucker
Clin. Transl. Neurosci. 2022, 6(3), 18; https://doi.org/10.3390/ctn6030018 - 21 Jul 2022
Cited by 1 | Viewed by 2526
Abstract
Number and picture rapid automatized naming (RAN) tests are useful sideline diagnostic tools. The main outcome measure of these RAN tests is the completion time, which is prolonged with a concussion, yet yields no information about eye movement behavior. We investigated eye movements [...] Read more.
Number and picture rapid automatized naming (RAN) tests are useful sideline diagnostic tools. The main outcome measure of these RAN tests is the completion time, which is prolonged with a concussion, yet yields no information about eye movement behavior. We investigated eye movements during a digitized Mobile Universal Lexicon Evaluation System (MULES) test of rapid picture naming. A total of 23 participants with a history of concussion and 50 control participants performed MULES testing with simultaneous eye tracking. The test times were longer in participants with a concussion (32.4 s [95% CI 30.4, 35.8] vs. 26.9 s [95% CI 25.9, 28.0], t=6.1). The participants with a concussion made more saccades per picture than the controls (3.6 [95% CI 3.3, 4.1] vs. 2.7 [95% CI 2.5, 3.0]), and this increase was correlated with longer MULES times (r = 0.46, p = 0.026). The inter-saccadic intervals (ISI) did not differ between the groups, nor did they correlate with the test times. Following a concussion, eye movement behavior differs during number versus picture RAN performance. Prior studies have shown that ISI prolongation is the key finding for a number-based RAN test, whereas this study shows a primary finding of an increased saccade number per picture with a picture-based RAN test. Number-based and picture-based RAN tests may be complimentary in concussion detection, as they may detect different injury effects or compensatory strategies. Full article
(This article belongs to the Special Issue Oto-Neuro-Ophthalmology (ONO))
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