Mediterranean Diet, Cardiovascular Diseases, Aging and Frailty

A special issue of Dietetics (ISSN 2674-0311).

Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 2563

Special Issue Editor

Special Issue Information

Dear Colleagues,

The current average life expectancy at birth is well over 80 years. Such high longevity in many cases is associated with the onset of chronic diseases and frailty. Cardiovascular disease still represents the first cause of mortality in the population; among the elderly, the most frequent pathological conditions are due to cardiovascular pathologies: for example, hypertension and heart failure. Maintaining an adequate nutrition status and lifestyle is important, both to reduce the risk of chronic diseases, and to slow or delay the onset of frailty. Dietary patterns such as the Mediterranean diet have been shown to reduce cardiovascular risk, to slow the aging process and to delay the onset of frailty, all characterized by chronic low-grade inflammation, by influencing chronic inflammatory processes and responses. This Special Issue of Dietetics entitled “Mediterranean Diet, Cardiovascular Diseases, Aging and Frailty” has been developed to compile contemporary research studies on this important topic. We invite you and your collaborators to consider the submission of your original research, protocol development and methodological studies, narrative or systematic reviews and meta-analyses. To better understand these complex relationships, we welcome all types of study designs in various populations, including large observational epidemiological studies, systematic reviews and meta-analyses, clinical and field trials and qualitative investigations.

Dr. Cristiano Capurso
Guest Editor

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Keywords

  • mediterranean diet
  • cardiovascular risk
  • cardiovascular disease
  • aging
  • frailty

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Published Papers (1 paper)

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Review

17 pages, 489 KiB  
Review
Cardioprotective Effects of Resveratrol in the Mediterranean Diet: A Short Narrative Review
by Cristiano Capurso, Francesco Bellanti, Aurelio Lo Buglio and Gianluigi Vendemiale
Dietetics 2023, 2(2), 174-190; https://doi.org/10.3390/dietetics2020014 - 26 May 2023
Cited by 3 | Viewed by 1966
Abstract
The beneficial effects of a Mediterranean diet are due to the numerous active compounds in the food and, particularly, the high concentration of compounds with synergistically acting antioxidant properties. Resveratrol, a stilbenoid nonflavonoid phenol, is an antioxidant that is naturally produced by numerous [...] Read more.
The beneficial effects of a Mediterranean diet are due to the numerous active compounds in the food and, particularly, the high concentration of compounds with synergistically acting antioxidant properties. Resveratrol, a stilbenoid nonflavonoid phenol, is an antioxidant that is naturally produced by numerous plants as a defensive agent in response to attacks from pathogens, such as bacteria and fungi. Resveratrol has several effects on human health, including on the lipid profile, where it primarily downregulates the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase, reducing the synthesis of cholesterol. Resveratrol also increases the expression of LDL receptors in the liver, contributing to the reduction in the LDL-cholesterol levels. This short narrative review, based on relevant articles written in English from a PubMed search, using the keywords “resveratrol”, “atherosclerosis”, “cardiovascular disease”, and “Mediterranean Diet“, focuses on the possible effects of this molecule on cardiovascular disease, lipid metabolism, and atherosclerosis. Full article
(This article belongs to the Special Issue Mediterranean Diet, Cardiovascular Diseases, Aging and Frailty)
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