Vaccination Strategies of COVID-19

A special issue of Epidemiologia (ISSN 2673-3986).

Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 56690

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la faculté de médecine, Université de Genève, 1205 Geneva, Switzerland
Interests: public policies; public innovation; global health; citizen participation
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Guest Editor
Institute of Global Health, Faculty of Medicine, University of Geneva, CH-1202, 8001 Geneva, Switzerland
Interests: epidemic modeling; structure and dynamics of complex systems; complex networks; modeling of social behavior
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
1. Swiss School of Public Health (SSPH+), Hirschengraben 82, 8001 Zürich, Switzerland
2. Institute of Global Health, Faculty of Medicine, University of Geneva, CH-1202, 8001 Geneva, Switzerland
Interests: global health; public health; travel and migrant health medicine; biomathematics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The COVID-19 vaccination program will be the world’s first public health intervention deployed on a global scale.

This Special Issue of original articles aims to consider and analyze country strategies to manage the deployment, implementation, and monitoring of the COVID-19 vaccination program.

In the context of public health emergencies, countries should strive for rational policies for the production, acquisition, and distribution of vaccines and related medical supplies in order to vaccinate the population in the most efficient way. In most countries, COVID-19 vaccination programs are under the responsibility of the ministry of health and monitored by other government authorities. The Special Issue will explore coordination mechanisms across all sectors of government and the participation of other stakeholders. The Special Issue will also look at national vaccination plans (NDVPs), specifically establishing how the plan is aligned with other national COVID-19 recovery and response measures and how interaction and communication with citizens have been established.

Investigation of the national strategies of vaccination within each country will be complemented with information on the specific characteristics of the available vaccines, vaccine supply volume and its dynamics, the current state of healthcare systems and clinical management, and the economic and social effects of the pandemic. When appropriate, papers will also address the challenges that countries have in acquiring vaccines through their relationships with pharma companies, international organizations, and countries supplying vaccines.

Prof. Dr. Michel Kazatchkine
Dr. Sana de Courcelles
Dr. Liudmila Rozanova
Prof. Dr. Antoine Flahault
Guest Editors

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Keywords

  • COVID-19
  • vaccination
  • national vaccination plan
  • healthcare system
  • vaccine diplomacy

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Published Papers (9 papers)

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Research

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18 pages, 4287 KiB  
Article
Between Ambitious Strategies and Reality: The African Union Strategy on COVID-19 Vaccine
by Amr ElAteek, Shimaa A. Heikal, Ludmila Rozanova and Antoine Flahault
Epidemiologia 2021, 2(4), 621-638; https://doi.org/10.3390/epidemiologia2040042 - 14 Dec 2021
Cited by 3 | Viewed by 3960
Abstract
A key learning lesson from country responses to COVID-19 pandemic was the impact of the strategies that are followed on combating the pandemic. Since the development of different vaccines and their supply globally, most countries have developed their own strategies to effectively provide [...] Read more.
A key learning lesson from country responses to COVID-19 pandemic was the impact of the strategies that are followed on combating the pandemic. Since the development of different vaccines and their supply globally, most countries have developed their own strategies to effectively provide sufficient doses for their population and start the vaccination process with the best outcomes. In this perspective, we review the African Union vaccination strategy by exploring the implementation of the strategy and its outcomes. We report on the strategy initiatives, vaccines distribution, administration, and the impact on new COVID-19 cases in African countries. Full article
(This article belongs to the Special Issue Vaccination Strategies of COVID-19)
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21 pages, 780 KiB  
Article
Analysing the Launch of COVID-19 Vaccine National Rollouts: Nine Case Studies
by John Gannon, Razieh Azari, Marta Lomazzi and Bettina Borisch
Epidemiologia 2021, 2(4), 519-539; https://doi.org/10.3390/epidemiologia2040036 - 23 Oct 2021
Cited by 1 | Viewed by 7181
Abstract
In late 2020 and early 2021, with the eagerly anticipated regulatory approval of vaccines against SARS-CoV-2, the urgent global effort to inoculate populations against this devastating virus was underway. These case studies examine the early stages of COVID-19 vaccine rollouts across nine regions [...] Read more.
In late 2020 and early 2021, with the eagerly anticipated regulatory approval of vaccines against SARS-CoV-2, the urgent global effort to inoculate populations against this devastating virus was underway. These case studies examine the early stages of COVID-19 vaccine rollouts across nine regions from around the world (Brazil, India, Indonesia, Ireland, Israel, Nigeria, Taiwan, United Kingdom and United States). By evaluating and comparing different approaches used to immunize against a novel pathogen, it is possible to learn a great deal about which methods were successful, and in which areas strategies can be improved. This information is applicable to the ongoing global vaccination against this virus, as well as in the event of future pandemics. Research was conducted by following and tracking the progress of vaccine rollouts in the nine regions, using published clinical trials, government documents and news reports as sources of data. Results relate to the proportion of populations that had received at least one COVID-19 dose by 28 February 2021. Outcomes are discussed in the context of three key pillars integral to all immunization programs: procurement of vaccines, communication with the public and distribution of doses to individuals. Full article
(This article belongs to the Special Issue Vaccination Strategies of COVID-19)
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24 pages, 1991 KiB  
Article
COVID-19 Vaccination Strategy in China: A Case Study
by Marjan Mohamadi, Yuling Lin, Mélissa Vuillet Soit Vulliet, Antoine Flahault, Liudmila Rozanova and Guilhem Fabre
Epidemiologia 2021, 2(3), 402-425; https://doi.org/10.3390/epidemiologia2030030 - 3 Sep 2021
Cited by 8 | Viewed by 7079
Abstract
The coronavirus disease 2019 (COVID-19) outbreak in China was first reported to the World Health Organization on 31 December 2019, after the first cases were officially identified around 8 December 2019. However, the case of an infected patient of 55 years old can [...] Read more.
The coronavirus disease 2019 (COVID-19) outbreak in China was first reported to the World Health Organization on 31 December 2019, after the first cases were officially identified around 8 December 2019. However, the case of an infected patient of 55 years old can probably be traced back on 17 November. The spreading has been rapid and heterogeneous. Economic, political and social impacts have not been long overdue. This paper, based on English, French and Chinese research in national and international databases, aims to study the COVID-19 situation in China through the management of the outbreak and the Chinese response to vaccination strategy. The coronavirus disease pandemic is under control in China through non-pharmaceutical interventions, and the mass vaccination program has been launched to further prevent the disease and progressed steadily with 483.34 million doses having been administered across the country by 21 May 2021. China is also acting as an important player in the development and production of SARS-CoV-2 vaccines. Full article
(This article belongs to the Special Issue Vaccination Strategies of COVID-19)
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17 pages, 1104 KiB  
Article
The Fast Approval and Slow Rollout of Sputnik V: Why Is Russia’s Vaccine Rollout Slower than That of Other Nations?
by Elza Mikule, Tuuli Reissaar, Jennifer Villers, Alain Simplice Takoupo Penka, Alexander Temerev and Liudmila Rozanova
Epidemiologia 2021, 2(3), 360-376; https://doi.org/10.3390/epidemiologia2030027 - 17 Aug 2021
Cited by 2 | Viewed by 5541
Abstract
The emergence of the SARS-CoV-2 pandemic in the beginning of 2020 led to the deployment of enormous amounts of resources by different countries for vaccine development, and the Russian Federation was the first country in the world to approve a COVID-19 vaccine on [...] Read more.
The emergence of the SARS-CoV-2 pandemic in the beginning of 2020 led to the deployment of enormous amounts of resources by different countries for vaccine development, and the Russian Federation was the first country in the world to approve a COVID-19 vaccine on 11 August 2020. In our research we sought to crystallize why the rollout of Sputnik V has been relatively slow considering that it was the first COVID-19 vaccine approved in the world. We looked at production capacity, at the number of vaccine doses domestically administered and internationally exported, and at vaccine hesitancy levels. By 6 May 2021, more first doses of Sputnik V had been administered abroad than domestically, suggesting that limited production capacity was unlikely to be the main reason behind the slow rollout. What remains unclear, however, is why Russia prioritized vaccine exportation. We provide three hypotheses that may contribute to explaining the slow domestic rollout: a generalized vaccine distrust among the Russian population, a desire to help less technologically advanced nations, and possible geopolitical incentives. Full article
(This article belongs to the Special Issue Vaccination Strategies of COVID-19)
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22 pages, 452 KiB  
Article
The COVID-19 Vaccination Strategy in Brazil—A Case Study
by Llanos Bernardeau-Serra, Agathe Nguyen-Huynh, Lara Sponagel, Nathalia Sernizon Guimarães, Raphael Augusto Teixeira de Aguiar and Milena Soriano Marcolino
Epidemiologia 2021, 2(3), 338-359; https://doi.org/10.3390/epidemiologia2030026 - 12 Aug 2021
Cited by 17 | Viewed by 10266
Abstract
Brazil is among the countries which have faced two devastating infection waves of COVID-19 in the past year. Despite the fact the country has one of the world’s leading immunization programs, Brazil only slowly established a national COVID-19 vaccination strategy and campaign. This [...] Read more.
Brazil is among the countries which have faced two devastating infection waves of COVID-19 in the past year. Despite the fact the country has one of the world’s leading immunization programs, Brazil only slowly established a national COVID-19 vaccination strategy and campaign. This case study is based on an integrative review of primary and secondary literature sources. Different search strategies on Medline and Google Scholar were performed for the case presentation, for the management and outcome of the COVID-19 outbreak and for the state of the COVID-19 vaccination program. Official documents from the Brazilian Ministry of Health, the website of the World Health Organization and pharmaceutical companies were also reviewed. Searches were limited to English, French, German, Portuguese and Spanish. This article describes the Brazilian COVID-19 vaccination campaign and the drivers and barriers to its implementation; and evaluates further investigations needed to have a conclusive overview over the constantly evolving situation. Healthcare inequalities, which were widened during the pandemic, a lack of coordination at the federal level, the absence of federal government support for scientific research and the lack of endorsement and commitment to the mitigation of the COVID-19 pandemic set the country’s COVID-19 vaccination campaign off to a challenging start. However, Brazil had a well-developed primary care system and national vaccination program prior to the pandemic, which are both important facilitators. At the time of writing, six vaccines are currently available in the country, and the program is advancing. The scientific community needs to continue to investigate the country’s vaccination strategy and its implementation to make sure that maximum effort is undertaken for the health of the Brazilian population. Full article
(This article belongs to the Special Issue Vaccination Strategies of COVID-19)

Review

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14 pages, 2840 KiB  
Review
Vaccination Is Not Enough: Understanding the Increase in Cases of COVID-19 in Chile despite a High Vaccination Rate
by Sabrina Lanzavecchia, Katharina Johanna Beyer and Sophie Evina Bolo
Epidemiologia 2021, 2(3), 377-390; https://doi.org/10.3390/epidemiologia2030028 - 24 Aug 2021
Cited by 5 | Viewed by 3936
Abstract
Chile, an OECD country in the southern hemisphere, surprised the world with a high speed COVID-19 vaccination rate at the beginning of 2021. Despite this, cases reached a record high again in April 2021, and the country went back to a state of [...] Read more.
Chile, an OECD country in the southern hemisphere, surprised the world with a high speed COVID-19 vaccination rate at the beginning of 2021. Despite this, cases reached a record high again in April 2021, and the country went back to a state of emergency. The reasons for this are multiple, complex, and interconnected. A feeling of false safety with the beginning of vaccination, the appearance of new more transmissible variants, too early relaxation of non-pharmacological measures at a point of vaccination below herd immunity, and vaccination in a high prevalence setting, appear to be main reasons for the resurgence. However, the political context and the socio-economic inequalities in Chile also play an important role, and are more difficult to measure and to compare with other countries. In conclusion, the Chilean example is a warning sign not to count on vaccination figures alone, and to maintain some of the previous non-pharmaceutical strategies to contain the pandemic. Full article
(This article belongs to the Special Issue Vaccination Strategies of COVID-19)
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Other

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21 pages, 370 KiB  
Case Report
What Can Be Learned from the Early Stages of the COVID-19 Vaccination Rollout in Australia: A Case Study
by Juliette Caroline Choiseul, Paris Jade Emmerson, Turan Eslanloo Pereira, Seyed-Moeen Hosseinalipour and Jennifer Hasselgård-Rowe
Epidemiologia 2021, 2(4), 587-607; https://doi.org/10.3390/epidemiologia2040040 - 3 Dec 2021
Cited by 5 | Viewed by 5526
Abstract
This paper addresses the SARS-CoV-2 vaccination progress in Australia. Globally, Australia was initially praised for its national COVID-19 response, reflecting well with regard to case numbers and mortality rates. However, Australia’s progress with its vaccine rollout has come under scrutiny. When compared globally, [...] Read more.
This paper addresses the SARS-CoV-2 vaccination progress in Australia. Globally, Australia was initially praised for its national COVID-19 response, reflecting well with regard to case numbers and mortality rates. However, Australia’s progress with its vaccine rollout has come under scrutiny. When compared globally, it fares very low in terms of the number of vaccine doses administered. This paper discusses the first three months of the vaccination process, and the challenges Australia faced during that time. Through an extensive literature review, data was collected on relevant topics concerning all aspects of the Australian COVID-19 situation. The following key points are discussed: the specific COVID-19 organisation at the federal vs. the state government levels, the Australian economy, the vaccine supply strategy, and the vaccine priority roll out. In conclusion, we highlight the impact of Australia initially relying heavily on the AstraZeneca vaccine, which subsequently came under fire regarding safety issues likely linking the vaccine to thrombosis with thrombocytopenia syndrome (TTS). Full article
(This article belongs to the Special Issue Vaccination Strategies of COVID-19)
17 pages, 2651 KiB  
Case Report
Addressing Different Needs: The Challenges Faced by India as the Largest Vaccine Manufacturer While Conducting the World’s Biggest COVID-19 Vaccination Campaign
by Cinja Nadana Koller, Cléo Josephine Schwerzmann, Alexia Suzanne Aimée Lang, Eleni Alexiou and Jaya Krishnakumar
Epidemiologia 2021, 2(3), 454-470; https://doi.org/10.3390/epidemiologia2030032 - 17 Sep 2021
Cited by 7 | Viewed by 5621
Abstract
The COVID-19 pandemic has highlighted some of the challenges that countries face when balancing domestic and global necessities, for example with regard to vaccine needs, production and distribution. As India hosts one of the world’s largest vaccine manufacturing industries and has one of [...] Read more.
The COVID-19 pandemic has highlighted some of the challenges that countries face when balancing domestic and global necessities, for example with regard to vaccine needs, production and distribution. As India hosts one of the world’s largest vaccine manufacturing industries and has one of the most extensive vaccination strategies, the country is particularly exposed to these challenges. This has become all the more obvious as the country experienced a second pandemic wave in the first half of 2021, which has led to a total ban on exports of COVID-19 vaccines. An analysis of the national vaccination strategy and the domestic vaccine industry through review of peer-reviewed literature, grey literature, and news reports showed the fragile balance between domestic and international needs. A numerical comparison of India’s domestic COVID-19 vaccine needs, export agreements, and production capacities was conducted. It was found that at current production rates as of April 2021, meeting all of the needs and complying with all of the agreements would be impossible. Scale-ups in production, as promised by the industry, however, will enable the achievement of all targets in the long term. Full article
(This article belongs to the Special Issue Vaccination Strategies of COVID-19)
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29 pages, 3796 KiB  
Case Report
COVID-19 Outbreak Management and Vaccination Strategy in The United States of America
by Sara Aicha Amara, Estefany Daniella Díaz, Lakshmi Krishna Menon, Priyanka Singh, Liudmila Rozanova and Antoine Flahault
Epidemiologia 2021, 2(3), 426-453; https://doi.org/10.3390/epidemiologia2030031 - 10 Sep 2021
Cited by 1 | Viewed by 5800
Abstract
Four months after the first case of COVID-19 was reported in the United States, the SARS-CoV-2 virus had spread to more than 90% of all counties. Although the transmission of the virus can be grossly mitigated through non-pharmaceutical interventions and public health measures, [...] Read more.
Four months after the first case of COVID-19 was reported in the United States, the SARS-CoV-2 virus had spread to more than 90% of all counties. Although the transmission of the virus can be grossly mitigated through non-pharmaceutical interventions and public health measures, risks of future outbreaks, emergence of more infectious variants, and disruptions to socio-economic life will probably remain until effective vaccines are administered to large portions of the global population. An exceptional collaboration between governments and the scientific community has led to the authorization of eight vaccines globally for full use, four of which were funded and developed in the United States. In this paper, we contextualize epidemiological, political, and economic impacts of the COVID-19 vaccination strategy in the United States of America between 20 January 2020, to 5 May 2021, with a key focus on vaccine hesitancy and public-private partnerships. Full article
(This article belongs to the Special Issue Vaccination Strategies of COVID-19)
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