Targeting the Epigenetic Machinery to Enhance Cancer Immunotherapy
A special issue of Epigenomes (ISSN 2075-4655).
Deadline for manuscript submissions: closed (25 December 2020) | Viewed by 14497
Special Issue Editors
Interests: cancer; epigenetics; biomarkers; bioinformatics; signaling pathway
Interests: colorectal cancer; tumor-immmune interactions; cancer genetics and epigenetics; immunotherapy; biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer immunotherapy, such as immune checkpoint blockade, is effective against human cancer. However, only a subset of patients benefit from this novel therapy. It is, therefore, important to explore the mechanism behind this phenomenon. Recent evidence suggest that cancer cells may alter the epigenetic machinery, that controls RNA expression, for instance by DNA methylation and histon modifications, to evade the immune attack. In this special issue, we invite researchers to submit original research articles or reviews to uncover how targeting the epigenetic machinery can enhance cancer immunotherapy in human cancer.
Dr. Peter Kuppen
Prof. Michael Chan
Guest Editors
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