Hydrogel for Tissue Regeneration (2nd Edition)

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Applications".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 1045

Special Issue Editor


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Guest Editor
Department of Orthopedics and Rehabilitation, Carver College of Medicine, The University of Iowa, Iowa City, IA, USA
Interests: hydrogel; tissue regeneration; osteoarthritis; exosome; intervertebral disc degeneration; arthrofibrosis
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Special Issue Information

Dear Colleagues,

We are grateful to all authors, reviewers, and readers for their responses to the first edition of “Hydrogel for Tissue Regeneration”. You can access these articles at no cost via the following link:

https://www.mdpi.com/journal/gels/special_issues/JW3AK7GIB9

Hydrogels have most commonly been used as a scaffold for tissue regeneration due to their potential to stimulate the construction of an extracellular matrix via a distinct three-dimensional structure and to deliver drugs, stem/progenitor cells, and extracellular vesicles/exosomes. This Special Issue, entitled “Hydrogel for Tissue Regeneration (2nd Edition)”, aims to collect high-quality research and review articles in all fields of gel materials, with a focus on the application of tissue regeneration and engineering. Since the aim of this Special Issue is to illustrate selected works and advances in research into hydrogel materials science, we encourage materials scientists, chemists, or clinical investigators to contribute papers reflecting the latest progress in their research fields. As Guest Editors, we kindly invite you to contribute a research or review paper on any topic related to this Special Issue, including, but not limited to, the following:

  • New development and characterization of hydrogels;
  • Tissue regeneration/engineering;
  • Delivery of stem/progenitor cells, drugs, RNA, DNA, gene, and extracellular vesicles/exosomes;
  • Three-dimensional printing, electrospinning, and molding-based injectable gels.

Dr. Dongrim Seol
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hydrogel
  • tissue regeneration/engineering
  • stem/progenitor cells
  • drugs
  • RNA
  • DNA
  • gene
  • extracellular vesicles/exosomes
  • 3D printing
  • electrospinning
  • molding-based injectable gels

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Published Papers (1 paper)

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Review

31 pages, 9924 KiB  
Review
Hyaluronic Acid-Based Dynamic Hydrogels for Cartilage Repair and Regeneration
by Mingshuo Zhang, Qianwen Ye, Zebo Zhu, Shuanglian Shi, Chunming Xu, Renjian Xie and Yumei Li
Gels 2024, 10(11), 703; https://doi.org/10.3390/gels10110703 - 30 Oct 2024
Viewed by 856
Abstract
Hyaluronic acid (HA), an important natural polysaccharide and meanwhile, an essential component of extracellular matrix (ECM), has been widely used in tissue repair and regeneration due to its high biocompatibility, biodegradation, and bioactivity, and the versatile chemical groups for modification. Specially, HA-based dynamic [...] Read more.
Hyaluronic acid (HA), an important natural polysaccharide and meanwhile, an essential component of extracellular matrix (ECM), has been widely used in tissue repair and regeneration due to its high biocompatibility, biodegradation, and bioactivity, and the versatile chemical groups for modification. Specially, HA-based dynamic hydrogels, compared with the conventional hydrogels, offer an adaptable network and biomimetic microenvironment to optimize tissue repair and the regeneration process with a striking resemblance to ECM. Herein, this review comprehensively summarizes the recent advances of HA-based dynamic hydrogels and focuses on their applications in articular cartilage repair. First, the fabrication methods and advantages of HA dynamic hydrogels are presented. Then, the applications of HA dynamic hydrogels in cartilage repair are illustrated from the perspective of cell-free and cell-encapsulated and/or bioactive molecules (drugs, factors, and ions). Finally, the current challenges and prospective directions are outlined. Full article
(This article belongs to the Special Issue Hydrogel for Tissue Regeneration (2nd Edition))
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