Pharmacogenetics of Psychiatric Diseases
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: closed (20 October 2024) | Viewed by 715
Special Issue Editor
Interests: pharmacogenetics; precision medicine; psychiatry; genetic markers; rare variants; PRS; molecular pathway analysis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Pharmacogenetics holds promise for a near Copernican revolution in psychiatry, where the current guideline-based, trial-and-error strategy has been known to lead to periods of untreated disorders, poor compliance, and various side effects. Pharmacogenetics, moreover, holds the potential to contribute to scientific development by allowing precision medicine to become the common treatment strategy in hospitals. The relevance of this field has been supported by emerging international guidelines in pharmacogenetics. However, implementable results, especially in the field of pharmacodynamics, currently lag behind expectations. There are numerous internationally coordinated initiatives underway to remove obstacles facing the application of pharmacogenetics in psychiatry. Nevertheless, the clinical diversity in therapy outcomes that has been found can only be partially explained by the validated pharmacogenomic markers that are already in place. It is necessary, therefore, to conduct additional research.
Given this knowledge, original research, reviews, and creative means of covering a variety of pharmacogenetics-related subjects in psychiatry are welcome in this Special Issue. The use of pharmacogenetics in clinical practice, the development of legislative tools and infrastructure related to pharmacogenetics, the search for novel pharmacogenetic markers specific to psychiatric treatments, the importance of epigenetics and rare genetic variants in pharmacogenetics, and innovative protocols for pharmacogenetic research are just a few of the subjects welcome.
Dr. Antonio Drago
Guest Editor
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Keywords
- pharmacogenetics
- precision medicine
- psychiatry
- genetic markers
- rare variants
- PRS
- molecular pathway analysis
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