Telomeres in Development, Senescence and Genome Instability: 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 30 March 2025 | Viewed by 34
Special Issue Editor
Special Issue Information
Dear Colleagues,
Telomere biology, as a special area of biology, was identified1971–1973 by Alexey Olovnikov (1936–2022) through his research on the under-replication of the ends of linear chromosomes. In his telomeric theory of aging, Alexey Olovnikov also determined the key roles of telomeres in various fundamental processes, such as cell death, cancer, and aging. Indeed, telomere functions are closely linked to many cellular processes, in particular through telomere signalling mechanisms, although their molecular basis remains poorly understood. Telomere shortening and telomere dysfunction are hallmarks of cellular senescence, aging and oncogenesis, highlighting the importance of the telomere state in genome stability. This Special Issue will compile research and methodological articles, reviews, and the opinions of authors regarding the diverse and fascinating field of telomere biology.
Topics include, but are not limited to, the following:
- Telomere disorders and cell death;
- Telomere factors as therapeutic targets in cancer;
- Telomeres and genome stability;
- Epigenetics of telomeres in development and aging;
- Mechanisms of telomere signalling;
- Telomeres in aging and senescence;
- Telomeropathies and laminopathies;
- Telomere protection mechanisms in development;
- Telomeres in non-model organisms;
- Telomere length control in germline and stem cells;
- Novel methods of telomere analysis.
Dr. Michal Zalzman
Guest Editor
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Keywords
- telomere disorders and cell death
- telomere factors as therapeutic targets in cancer
- telomeres and genome stability
- telomeres in aging and senescence
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