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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mechanisms of Neurotoxicity submission deadline 31 Jan 2025 | 10 articles | Viewed by 21893
Keywords: neuropathy; ion channels; voltage gated ion channels; pain; chemotherapy
(This special issue belongs to the Section Molecular Neurobiology)
70 Years of Oxytocin: Updates on Groundbreaking Findings 70 Years after the Discovery of Oxytocin
edited by
submission deadline 31 Jan 2025 | 5 articles | Viewed by 17315
Keywords: oxytocin; energy; metabolism; metabolic syndrome; skeletal muscle; bone; Prader– Willi syndrome; autism; body composition; thermoregulation
(This special issue belongs to the Section Molecular Biology)
The Interaction Between Cell and Virus, 2nd Edition
edited by
submission deadline 31 Jan 2025 | 7 articles | Viewed by 11494
Keywords: viral replication; gene expression; lytic infection; viral structure; viral assembly; cell signaling pathway; post-translational modification; immune evasion; viral tumorigenesis; antiviral medication
(This special issue belongs to the Section Molecular Microbiology)
Neurotrophins: Roles and Function in Human Diseases 2.0
edited by
submission deadline 31 Jan 2025 | 3 articles | Viewed by 7849
Keywords: neuroinflammation; brain; toxicology; cell growth; neurogenesis
(This special issue belongs to the Section Molecular Neurobiology)
Recent Advances in Bioseparation Technologies for the Capture of Emerging Biomacromolecules submission deadline 31 Jan 2025 | 3 articles | Viewed by 7032
Keywords: nucleic acids; proteins; purification; isolation
(This special issue belongs to the Section Macromolecules)
Interactions of Cells with Biomaterials for Regenerative Medicine, 4th Edition submission deadline 31 Jan 2025 | 5 articles | Viewed by 6503
Keywords: biomaterials; bioceramics; biopolymers; tissue engineering; bone scaffolds; wound dressings; skin substitutes; stem cells; cell culture models; cell-biomaterial interactions
(This special issue belongs to the Section Materials Science)
Mental Disorders and Translational Psychiatry: From Neurobiology to Therapeutic Perspective
edited by Lionella Palego and
submission deadline 31 Jan 2025 | 2 articles | Viewed by 6086
Keywords: mental disorders; illness heterogeneity; comorbidity; treatment resistance; neurobiology; applied neuroscience; translational psychiatry; peripheral biomarkers
(This special issue belongs to the Section Molecular Neurobiology)
Plant Extracts and Bioactive Molecules with Potential Benefits for Human Health submission deadline 31 Jan 2025 | 4 articles | Viewed by 6083
Keywords: medicinal plants; plant extracts; bioactive phytocompound identification and quantification; pharmacological activity; health benefits; phytotherapy; plant-based diet; functional foods
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Mechanisms of Endothelial Dysfunction: Fourth Edition
edited by
submission deadline 31 Jan 2025 | 5 articles | Viewed by 5285
Keywords: vascular permeability; atherosclerosis; blood– brain barrier; endothelial adhesion molecules; vasodilation; thrombosis
(This special issue belongs to the Section Molecular Immunology)
Abiotic Stress Tolerance and Genetic Diversity in Plants, 2nd Edition
edited by
submission deadline 31 Jan 2025 | 5 articles | Viewed by 4690
Keywords: biodiversity; molecular breeding; comparative genomics; abiotic stress adaptation; genetic mapping; predictive breeding; genomic prediction; assisted gene flow; plant breeding; restoration ecology; conservation genetics
(This special issue belongs to the Section Molecular Plant Sciences)
New Insights in Prion Diseases
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 4665
Keywords: prion diseases; prion mutation; genetic modifier; neurodegenerative diseases; therapy; neuroprotection
(This special issue belongs to the Section Molecular Neurobiology)
New Molecular Mechanisms in the Development of Brain Tumors and Metastases submission deadline 31 Jan 2025 | 2 articles | Viewed by 4589
Keywords: brain tumor; brain metastasis; blood– brain barrier; target therapy; cancer molecular biology; brain tumor microenvironment; molecular biomarkers
(This special issue belongs to the Section Molecular Oncology)
Drug Discovery: Design, Synthesis and Activity Evaluation submission deadline 31 Jan 2025 | 4 articles | Viewed by 4462
Keywords: drug design; organic synthesis; biological activity evaluation; biologically active compounds; diagnostic/therapeutic agents; labeled ligands; structure– activity relationships (SARs); structural biological studies; computational studies; pharmacokinetics/pharmacodynamics; drug delivery
(This special issue belongs to the Section Molecular Pharmacology)
Abiotic Stresses in Plants: From Molecules to Environment—2nd Edition
edited by
submission deadline 31 Jan 2025 | 4 articles | Viewed by 4100
Keywords: stress signaling; abiotic stress; oxidative stress; genotoxic stress
(This special issue belongs to the Section Molecular Plant Sciences)
Neurodegenerative Disease: From Molecular Basis to Therapy, 3rd Edition
edited by
submission deadline 31 Jan 2025 | 2 articles | Viewed by 3773
Keywords: neurodegenerative diseases; molecular biology; neurogenetics; pathogenesis; therapy; personalized medicine
(This special issue belongs to the Section Molecular Neurobiology)
Molecular and Cellular Mechanisms in Reproduction
edited by and Eun Mi Chang
submission deadline 31 Jan 2025 | 1 articles | Viewed by 3198
Keywords: mammalian reproduction; uterine biology; oogenesis; spermatogenesis; meiosis; embryo development; uterine implantation; endometrial regeneration; ovarian aging; endometriosis; ovarian cancer; testicular cancer; uterine cancer; cervical cancer; menopause
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Advances in Tea Tree Genetics and Breeding: 2nd Edition
edited by and
submission deadline 31 Jan 2025 | 2 articles | Viewed by 3179
Keywords: tea plant (Camellia sinensis); molecular mechanism; secondary metabolites; stress response; quality-related component; genes identification; QTL mapping; molecular functional markers
(This special issue belongs to the Section Molecular Plant Sciences)
Targeted Delivery of Nucleic Acids
edited by Yong-Serk Park
submission deadline 31 Jan 2025 | 2 articles | Viewed by 3079
Keywords: nucleic acid delivery; gene delivery; pDNA delivery; siRNA delivery; miRNA delivery; mRNA delivery; CRISPR-Cas delivery; nanoparticle; lipid nanoparticle; targeted therapy
(This special issue belongs to the Section Molecular Biology)
Molecular Insights into Zoology
edited by
submission deadline 31 Jan 2025 | 3 articles | Viewed by 2840
Keywords: zoology; genomics; transcriptomics; phylogeny; molecular evolution; mtDNA; eDNA; RNA; molecular zoolog
(This special issue belongs to the Section Molecular Biology)
Oxidative Stress and Inflammation in Health and Disease
edited by Fabio Vivarelli and
submission deadline 31 Jan 2025 | 2 articles | Viewed by 2528
Keywords: oxidative stress; inflammation; chronic diseases; risk factors; prevention
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
From Diagnosis to Treatment of Haematological Neoplasms submission deadline 31 Jan 2025 | 2 articles | Viewed by 2508
Keywords: haematological neoplasms; biomarkers; precision medicine
(This special issue belongs to the Section Molecular Oncology)
Molecular Mechanisms of Cardiotoxicity
edited by
submission deadline 31 Jan 2025 | 2 articles | Viewed by 2403
Keywords: cardiac dysfunction; cardiotoxicity; atrophy; antagomiR; AAV; gene therapy; heart failure; oxidative stress; apoptosis; myocardial remodeling
(This special issue belongs to the Section Molecular Toxicology)
Vegetable Genetics and Genomics, 3rd Edition
edited by and
submission deadline 31 Jan 2025 | 3 articles | Viewed by 2399
Keywords: major vegetable crops; genome; variome; genotyping; GWAS; QTL mapping; functional genome; metabolome; breeding target characters; genetic mechanism; functional genes
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Pathologies and Treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 2283
Keywords: myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); diagnosis; post-exertional malaise (PEM); comorbidity; biomarker; therapy; immunity; microbiome
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research Progress of Cereal Crop Disease Resistance
edited by and Zhenqi Su
submission deadline 31 Jan 2025 | 3 articles | Viewed by 2232
Keywords: cereal crops; disease resistance; resistance genes; breeding; molecular marker-assisted selection; molecular regulatory network
(This special issue belongs to the Section Molecular Plant Sciences)
Applications of Stem Cells and Extracellular Vesicles in Regenerative Medicine submission deadline 31 Jan 2025 | 1 articles | Viewed by 2123
Keywords: regenerative medicine; pluripotent stem cells; cell differentiation; tissue engineering; gene editing; therapeutic potential; clinical applications; neurodegenerative disorders; disease modeling
(This special issue belongs to the Section Molecular Biology)
Advances in Density Functional Theory and Related Methods for Molecular Computational Chemistry
edited by Paolo Umari
submission deadline 31 Jan 2025 | 1 articles | Viewed by 2107
Keywords: density functional theory; quantum chemistry; algorithms; quantum computing; high-performance computing; machine learning; many-body perturbations theory; quantum Monte Carlo
(This special issue belongs to the Section Molecular Informatics)
Molecular Aspects of Forensic Toxicology
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1942
Keywords: forensic toxicology; molecular mechanism; toxicological biomarkers; post-mortem interval; in vitro; in vivo; and in silico models; new psychoactive substances (NPSs); new synthetic opioids; liquid chromatography-high resolution mass spectrometry (LC-HRMS/MS); liquid chromatography-tandem mass spectrometry (LC-MS/MS) and gas chromatography-tandem mass spectrometry (GC-MS/MS)
(This special issue belongs to the Section Molecular Toxicology)
Molecular Mechanism and Therapy of Psoriasis
edited by
submission deadline 31 Jan 2025 | 2 articles | Viewed by 1913
Keywords: psoriasis; inflammatory skin disease; cytokine; innate lymphoid cell; systemic inflammation; JAK inhibitor; small molecule
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Pathogenicity and Antibiotic Resistance of Helicobacter pylori
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1777
Keywords: Helicobacter pylori; antibiotic resistance; antibiotic tolerance; point mutations; efflux pumps; biofilm formation; coccoid forms; membrane vesicles; virulence factors
(This special issue belongs to the Section Molecular Microbiology)
Evolution and Genomics: Relevance to Current Issues
edited by and Sally Lloyd
submission deadline 31 Jan 2025 | 2 articles | Viewed by 1765
Keywords: paralogy; synteny; evolution; genomics; duplication; haplotype
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Biology of Senescence and Anti-Aging Strategies submission deadline 31 Jan 2025 | 1 articles | Viewed by 1736
Keywords: cellular senescence; aging; delaying senescence; aging-associated diseases
(This special issue belongs to the Section Molecular Biology)
Natural Compounds for Counteracting GI and Liver Diseases submission deadline 31 Jan 2025 | 3 articles | Viewed by 1614
Keywords: natural compounds; gastrointestinal diseases; liver diseases; pharmacological potential
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Positron Annihilation Spectroscopies in Condensed Matter
edited by and Chunqing He
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1593
Keywords: defects; Doppler broadening of the annihilation radiation lineshape; free volume; porous materials; positron annihilation lifetime spectroscopy; vacancy; vacancy clusters
(This special issue belongs to the Section Macromolecules)
Advances in Stem Cell-Based Regenerative Medicine for Renal Disorders
edited by In-Yong Kim
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1575
Keywords: chronic kidney disease; acute kidney injury; stem cells; regenerative medicine; stem cell therapy; cellular reprogramming; cell transplantation
(This special issue belongs to the Section Molecular Biology)
Advances in Antibody–Drug Conjugates
edited by Bing Sun
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1415
Keywords: antibody– drug conjugate (ADC); cancer treatment; non-oncology indications; antibody selection; payload; linker; conjugation chemistry
(This special issue belongs to the Section Molecular Immunology)
Molecular Dynamics Simulations and Structural Analysis of Protein Domains (2nd Edition) submission deadline 31 Jan 2025 | 1 articles | Viewed by 1345
Keywords: protein structures; molecular dynamics; advanced molecular dynamics; variants; pathologies; drug design; allostery; protein domains; secondary structures; methodological development; protein design; ligands; normal mode analysis; machine learning
(This special issue belongs to the Section Molecular Informatics)
Electrochemistry: Molecular Advances and Challenges
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1332
Keywords: fundamental electrochemistry; electroanalytical techniques; sensors and biosensors; nano-electrochemistry; electrochemical energy production and storage; environmental electrochemistry
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Emerging Roles for Serotonin in Regulating Metabolism submission deadline 31 Jan 2025 | 1 articles | Viewed by 1254
Keywords: serotonin; cortisol; phospholipids; glycosaminoglycans; oxidative stress; veterinary anesthesia and analgesia
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Insights into Zoonotic Diseases submission deadline 31 Jan 2025 | 1 articles | Viewed by 1205
Keywords: mycobacterial diseases; bubonic and pneumonic plague; Q fever; cat scratch disease; Mediterranean fever; HIV; malaria; ADIS; SARS-CoV-2; adjunctive therapy; immune-enhancing agents; antimycobacterial compounds; host-directed therapies; pathogenesis; modulation of host immune responses
(This special issue belongs to the Section Molecular Microbiology)
New Molecular Insights and Therapeutic Strategies for Ocular Vascular Pathologies
edited by Raquel Lima e Silva
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1199
Keywords: VEGF pathway; anti-VEGF therapy; retinal neovascularization; choroidal neovascularization; oxidative stress
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research and Cellular Biology of Breast Cancer submission deadline 31 Jan 2025 | 1 articles | Viewed by 1162
Keywords: molecular mechanisms of tumor growth and diffusion; cancer cell biology; biology of tumor micro-environmental cells; MDR; hormone dependency; HER2 positive breast cancer; TNBC; genetic and epigenetic alterations; pro-tumor and anti-tumor immune responses; conventional and biological therapies; blood and tissue biomarkers
(This special issue belongs to the Section Molecular Oncology)
Application of Artificial Intelligence in Molecular Sciences
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1061
Keywords: artificial intelligence; deep learning; algorithms; molecular modeling and simulation; materials discovery; analysis of biological sequence data; computational chemistry; bioinformatics; genomics; protein structure prediction; molecular dynamics simulation
(This special issue belongs to the Section Molecular Informatics)
Bio-Nano Interactions—3rd Edition
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1049
Keywords: nanoparticles; proteins; smart nanomaterial surfaces; selective protein binding; nanomaterials; abiotic material; biological systems; bio-inspired inorganic materials and DNA nanotechnologies
(This special issue belongs to the Section Molecular Nanoscience)
Medicinal Plants and Natural Compounds in Health and Disease: Progresses, Challenges, Opportunities, 2nd Edition submission deadline 31 Jan 2025 | 1 articles | Viewed by 1033
Keywords: medicinal plants; phytochemicals; vitamins; oxidative stress; gene expression; protein expression; cellular signaling; ethnopharmacology
(This special issue belongs to the Section Molecular Pharmacology)
The Roles of Phytochemicals in Neuroprotective Mechanism
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1020
Keywords: phytochemicals; pharmaceuticals; biochemistry; neuroprotection
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Autoimmune Diseases: From Molecular Basis to Therapy
edited by Raquel López-Mejías
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1018
Keywords: genetics; epigenetics; molecules; autoimmune diseases; inflammation; cell-mediated immunity
(This special issue belongs to the Section Molecular Immunology)
From Genes to Medicine: Exploring the Genetic and Biological Bases of Medicinal Plants
edited by Wajid Zaman
submission deadline 31 Jan 2025 | 1 articles | Viewed by 975
Keywords: medicinal plants; genetic diversity; biosynthesis pathways; bioactive compounds; genomic technologies; plant breeding; biotechnology; CRISPR; phytochemistry; pharmacology; drug discovery; plant-based therapies
(This special issue belongs to the Section Molecular Biology)
Hemophilia: From Pathophysiology to Novel Therapies
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 934
Keywords: hemophilia; novel therapy in hemophilia; ultra-long half life clotting factor; clotting factor mimics; coagulation rebalancing agent; gene therapy; pathogenesis of hemophilia; molecular biology of hemophilia
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research on Diabetes and Obesity
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 926
Keywords: obesity; diabetes; hypothalamus; insulin resistance; glucose homeostasis; lipid metabolism; adipose tissue; cardiovascular tissue
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
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