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Molecular Research on Tumor Suppressor Proteins

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 129

Special Issue Editor


E-Mail Website
Guest Editor
Department of Microbiology and Molecular Genetics, University of California Davis, One Shields Ave., Davis, CA 95616, USA
Interests: DNA repair; homologous recombination; BRCA1/BRCA2; Rad51; Rad51 paralogs

Special Issue Information

Dear Colleagues,

DNA repair pathways are crucial for maintaining genome integrity and preventing tumorigenesis. Defective DNA repair factors can result in DNA abnormalities and irregular cell growth. Tumor suppressors such as BRCA1/BRCA2, PALB2, and RAD51C play essential roles in homologous recombination, a high-fidelity DNA repair pathway. This Special Issue aims to showcase recent research advances in the molecular mechanisms of tumor suppressor proteins in DNA repair pathways.

In this Special Issue of the International Journal of Molecular Sciences, we are calling for original research articles, reviews, and perspectives focusing on the molecular mechanisms underlying the essential functions of tumor suppressor proteins involved in DNA repair pathways. We are particularly interested in cellular, biochemical, and structural investigations of these DNA repair proteins, as well as contributions that focus on innovative research facilitating drug discovery and patient treatments.

We are seeking a diverse collection of high-quality original articles with in-depth analysis for this Special Issue. The focus is on enhancing our understanding of the intricate molecular strategies employed by DNA repair-related tumor suppressors to prevent genome abnormality and tumor formation. Your contributions to this Special Issue are welcome.

Dr. Jie Liu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • DNA repair
  • genome stability
  • tumor suppressor
  • BRCA1
  • BRCA2
  • PALB2
  • RAD51C

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Published Papers

This special issue is now open for submission.
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