Role of Extracellular Vesicles in Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 190
Special Issue Editors
Interests: autoimmune disease; neuroinflammation; immuno-oncology; aging
2. Translational Radiation Oncology, National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), Heidelberg, Germany
Interests: extracellular vesicles; cancer; miRNA; biomarkers; liquid biopsy; immuno-oncology; radiotherapy
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) have emerged as crucial mediators of intercellular communication, carrying a diverse cargo that includes nucleic acids, proteins, metabolites, microRNAs (miRNAs), and even whole organelles like mitochondria. These vesicles play a pivotal role in the pathophysiology of a wide range of diseases, including cancer, neurodegenerative disorders, cardiovascular diseases, and autoimmune conditions. By facilitating the transfer of bioactive molecules between cells, EVs contribute to disease progression, immune modulation, and tissue remodeling. Moreover, their cargo reflects the molecular signatures of the disease state, making EVs promising biomarkers for early detection, prognosis, and treatment monitoring. In addition to their diagnostic potential, EVs are also being explored as therapeutic targets and delivery vehicles, offering innovative strategies for precision medicine. This Special Issue brings together a collection of studies that highlight the multifaceted role of EVs in disease, from their molecular composition to their impact on cellular networks and organ systems. By exploring the mechanisms through which EVs contribute to disease pathophysiology, as well as their clinical potential as biomarkers and therapeutic agents, this issue underscores the importance of EVs in advancing our understanding of human health and disease.
Dr. Gorjana Rackov
Dr. Aoife Ward Gahlawat
Guest Editors
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Keywords
- extracellular vesicles (EVs)
- biomarkers
- disease pathophysiology
- miRNAs
- intercellular communication
- therapeutic targets
- mitochondrial transfer
- cancer
- neurodegenerative disorders
- precision medicine
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