New Advances in Molecular Research in Leukemia
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 141
Special Issue Editors
Interests: Immunotherapy for hematological cancers; hematopoietic stem cell transplantation; laboratory hematology; the immunological effects of phytochemicals; transfusion medicine; bone marrow failure
Special Issues, Collections and Topics in MDPI journals
Interests: hematology and oncology; microbe-induced carcinogenesis; cancer drug discovery; parasitic infections; opportunistic microorganisms; immunology; microbiota; infectious diseases; artificial intelligence and medical sciences
Special Issues, Collections and Topics in MDPI journals
Interests: signaling pathway; resistance; leukemia; cancer stem cells; apoptosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to invite you to contribute to this Special Issue entitled “New Advances on Molecular Research in Leukemia.”
According to recent reports, the incident cases of hematologic malignancies have been increasing worldwide since 1990, reaching nearly 1.35 million in 2019, and while the age-standardized death rate (ASDR) for almost all types of hematologic malignancies is declining, leukemia remains the hematologic malignancy with the highest incidence and mortality, with an ASDR of 4.26 per 100,000 people in 2019. Among the highly heterogenous leukemia types, from 1990 to 2019, chronic myeloid leukemia (CML) was the type of leukemia with a decreased age-standardized incidence rate (AISR), while acute myeloid leukemia (AML) was the type of leukemia with an increased ADSR. Nevertheless, our understanding of the biology of leukemias is progressing rapidly, and novel therapeutic agents have been approved for various indications in leukemia. Moreover, accelerated advances in personalized medicine and genomics have contributed significantly to improving the diagnosis, classification, risk stratification, and management of leukemias. Furthermore, the introduction of new classes of targeted therapies and refinements in measurable residual disease (MRD) testing has changed the standard of care for patients with these malignancies. This Special Issue aims to explore recent advances in all types of leukemias, including AML, acute lymphoblastic leukemia (ALL), blastic plasmacytoid dendritic cell neoplasm (BPDCN), myelodysplastic neoplasm (MDS), myeloproliferative neoplasm (MPN), CML, and chronic lymphocytic leukemia (CLL).
We welcome the submission of original research articles, reviews, and commentaries. Research areas may include (but are not limited to) the following: leukemogenesis, disease classification, prognostic factors, measurable residual disease (MRD), biomarkers of treatment response, targeted therapies, experimental agents, and clinical trials.
Prof. Dr. Akiyoshi Takami
Dr. Jorge Luis Espinoza
Guest Editors
Manuscript Submission Information
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Keywords
- acute lymphoblastic leukemia (ALL)
- chronic lymphocytic leukemia (CLL)
- acute myelogenous leukemia (AML)
- chronic myelogenous leukemia (CML)
- hairy cell leukemia (HCL)
- T-cell prolymphocytic leukemia (T-PLL)
- large granular lymphocytic leukemia
- measurable residual disease (MRD)
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