Molecular Research on Tumor Metastasis and Inhibition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 March 2025 | Viewed by 42
Special Issue Editor
Interests: cancer metabolism; radiobiology; biomolecular imaging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are proposing a Special Issue on “Molecular Research on Tumor Metastasis and Inhibition”.
Cancer metastasis is one of the hallmarks of cancer. It is a symbol and an important event for tumor cells. In this process, tumor cells use their abilities to migrate/invade, and some cells may undergo morphological changes. At the same time, the secretion of matrix metalloproteinase, changes in the cytoskeleton, and destruction of the basement membrane will follow. At this stage, the overall microenvironment becomes hypoxic, acidic, and angiogenic. Therefore, based on the above, tumor metastasis represents an advanced stage of cancer progression with a poor survival rate, and more effective drugs and treatment options are urgently needed.
This Special Issue of IJMS aims to bring together a range of original research articles and reviews. Our focus is on pan-cancer, covering the diagnosis, treatment, and prognosis of metastatic events. Research on biomarker discovery, 'omic' approaches (such as genomics, proteomics, genomics, and transcriptomics), and many other areas is welcome. We also welcome the use of cells, animal models, and clinical specimens to study cancer metastasis events and the use of clinical regimens in combination with potential compounds/herbal drugs, peptides, or non-coding RNA to counteract their consequences. We expect these topics to improve current cancer treatments and to be at the forefront of drug development.
Dr. Yu-Chan Chang
Guest Editor
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Keywords
- metastasis
- epithelial–mesenchymal transition
- small-molecule compounds
- animal imaging
- signal transduction
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