G-protein Coupled Receptors
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 117
Special Issue Editor
Interests: cancer biology; neurogenerative diseases; aging; BBB; diabetes; peptide processing; G-protein coupled receptors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
G-protein-coupled receptors (GPCRs) are composed of 800 cell surface proteins that are characterized by seven transmembranes and, upon the activation of heterotrimeric G proteins, are involved in the regulation of signal transduction pathways. In the central nervous system, and in peripheral tissues, GPCRs modulate multiple neurotransmitters and hormones. At present, 40% of the clinically approved therapeutic drugs available on the market target GPCRs due to their crucial role in the regulation of several physiological cell functions. In the last 20 years, significant progress has been made in understanding GPCRs at the molecular and protein level, in addition to their functional cross-talk as homo- and heterodimers. IJMS, a high-impact journal of international renown, will be publishing a Special Issue on GPCRs, and we welcome submissions.
Dr. Ujendra Kumar
Guest Editor
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Keywords
- G-protein-coupled receptors
- GPCR
- therapeutic drugs
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