Role of EGFR in Colorectal Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 165
Special Issue Editor
Interests: colorectal cancer; organoids; immunology; KRAS mutation; molecular biology; flow cytometry; immunofluorescence; immunohistochemistry; EGFR pathway; metabolism; type 2 diabetes; obesity
Special Issue Information
Dear Colleagues,
Colorectal cancer (CRC) remains a significant global health burden. The epidermal growth factor receptor (EGFR) is a well-established target in cancer therapy, and its role in CRC is a topic of ongoing investigation. This Special Issue of the International Journal of Molecular Science aims to provide a comprehensive overview of the current knowledge on EGFR in CRC and its potential for therapeutic intervention.
Topics of Interest:
- EGFR overexpression and signaling pathways in CRC progression;
- The impact of RAS mutations on the efficacy of EGFR-targeted therapies;
- Novel strategies for targeting EGFR in CRC, including new drug combinations and personalized medicine approaches;
- Biomarkers for predicting response to EGFR-targeted therapy;
- Clinical trials of EGFR inhibitors in CRC;
- Resistance mechanisms to EGFR-targeted therapies and strategies for overcoming resistance;
- The role of the tumor microenvironment in EGFR signaling in CRC.
Dr. Verónica Moreno-Viedma
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- EGFR
- RAS
- biomarkers/prognosis
- resistance mechanisms
- tumor microenvironment
- EGFR signaling pathways
- EGFR inhibitors
- onco-immunology
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
