Neuroinflammation in Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 119
Special Issue Editor
2. Stem-Cell and Brain Research Institute, 18 Avenue du Doyen Lépine, F-69500 Bron, France
3. Lyon-Est School of Medicine, University Claude Bernard Lyon 1, 43 Bd du 11 Novembre 1918, F-69100 Villeurbanne, France
Interests: multiple sclerosis pathophysiology; CNS-targeted autoimmunity; neuroinflammation; computational data mining; systems biology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, the field of investigation covered by the study of neuroinflammation has expanded considerably. It includes not only the pathophysiological aspects of prototypical neuroinflammatory diseases, notably multiple sclerosis and Guillain–Barré syndrome, but also a large number of diseases involving a neuroinflammatory component. A non-exhaustive list of such disorders includes neurodegenerative diseases, stroke, brain trauma, neuroinfectious pathologies, and psychiatric disorders. Furthermore, neuroinflammatory mechanisms, defined as such by the involvement of immune molecules and/or cells, are also involved in both physiological brain functions and key neurodevelopmental stages. The cellular players in these neuroinflammatory mechanisms are numerous. They comprise genuine immune cells such as microglial cells and T lymphocytes as well as neural cells, which, although non-immune by nature, are indeed immunocompetent (astrocytes, oligodendrocytes, neurons). Considered an immunoprivileged site for a long time, the CNS should rather be apprehended as a site of “immunocomplexity”, whose keen understanding will require major research efforts. This Special Issue is open to researchers from a large panel of backgrounds who share a common interest in deciphering neuroinflammatory mechanisms in health and disease.
Prof. Dr. Serge Nataf
Guest Editor
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Keywords
- neuroinflammation
- multiple sclerosis
- Guillain–Barré syndrome
- neurodegenerative diseases
- immune molecules
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