Targeted Therapy of Cancer: Innovative Drugs and Molecular Tools
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 May 2025
Special Issue Editors
Interests: drug delivery; toxins; immune conjugates; cancer therapy; protein structure; protein toxins; immunotoxins; endocytosis
Special Issues, Collections and Topics in MDPI journals
Interests: transferrins; lactoferrin; ovotransferrin; saporin; ADCs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Modern medicine has focused its attention on the possibility of delivering drugs in a controlled manner, particularly as soon as more attractive targets have emerged, and new molecular tools have become available. Targeted cancer therapy has become an innovative strategy, with new drugs being constantly discovered and applied in the treatment of various types of tumors, enabling precision and personalized medicine. A major challenge concerns the safe delivery of drugs (minimizing side-effects) and the potential exploitation of novel molecular tools, such as miRNA, CRISPR-Cas9, aptamers, and EVs. These approaches complement the use of more classical methods, such as antibody-based therapies, which still require innovation to become more effective.
This Special Issue of the International Journal of Molecular Sciences aims to focus on the use of innovative drugs and molecular tools to target cancer cells in vivo, with particular attention to the mechanisms of action and the structural characteristics of novel therapeutic agents. We look forward to exploring all aspects of recent applications of cancer-targeted agents and biomaterials for controlled drug release. Contributions in the form of original research articles and reviews, focusing on the rational design, synthesis, and/or biological evaluation of various agents (including small molecules, nano-drugs, natural products, endogenous molecules, antibodies, vaccines, etc.) as potential cancer therapeutics, are welcome for submission to this Special Issue.
Prof. Dr. Rodolfo Ippoliti
Dr. Francesco Giansanti
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- drug delivery
- targeted therapies
- cancer therapy
- molecular targets
- precision medicine
- molecular therapeutic targets
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