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Methodological and Theoretical Analyses of the Contribution of Immediate Early Genes to the Understanding of Brain Processing of Stressors

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 20 March 2025 | Viewed by 191

Special Issue Editor


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Guest Editor
Institut de Neurociències, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain
Interests: PTSD; stress; endocrine; biological markers

Special Issue Information

Dear Colleagues,

Immediate early genes (IEGs) are considered biochemical markers of neuronal activation. Thus, their utilization allows researchers to identify neurons and brain areas activated by a wide range of stimuli, including stressors. The term’s definition encompasses genes whose expression does not require the synthesis of proteins. Most of these are transcription factors, although others codify for proteins with specific functional roles. While the use of IEGs has greatly contributed to the understanding of how the brain processes stimuli, less attention has been paid to methodological problems, factors involved in the differential expression of the various IEGs, and the relationship of IEGs with other strategies that assess neuronal activation in vivo.

This publication calls for papers dealing with these subjects, aiming to refine the use and interpretation of those studies via this fundamental strategy.

Dr. Antonio Armario
Guest Editor

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Keywords

  • immediate early genes
  • neuron
  • brain activities
  • psychiatric disorder
  • memory

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