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Chelating Ligands in Therapeutics: Recent Advances and Future Directions

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 82

Special Issue Editors


E-Mail Website
Guest Editor
Department of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133 Milano, Italy
Interests: diffraction techniques; structure elucidation; conformation of bioactive compounds; antitubercular and anticancer agents; metal complexes; protein–protein interaction inhibitors; enzymatic inhibitors; multi-target drugs
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Pharmaceutical Sciences, University of Milan, Via L. Mangiagalli 25, 20133 Milano, Italy
Interests: diffraction techniques; structure elucidation; conformation of bioactive compounds; antitubercular and anticancer agents; metal complexes; protein–protein interaction inhibitors; enzymatic inhibitors; multi-target drugs
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear colleagues,

We are excited to announce the launch of a Special Issue titled "Chelating Ligands in Therapeutics: Recent Advances and Future Directions". This issue will explore the growing significance of chelating ligands in modern drug design and development.

Chelating ligands play an increasingly important role in a wide range of therapeutic innovations, from metal chelation therapies to novel anticancer and antimicrobial agents. With the rising incidence of metal-related diseases and the shift toward precision medicine, the need for fresh research into chelators has never been greater.

We invite researchers and experts in medicinal chemistry, biochemistry, pharmacology, and related fields to contribute original research papers or critical reviews that highlight advancements in the use of chelating ligands for therapeutic interventions.

Contributions may focus on the design, synthesis, and development of novel chelating agents for the treatment of cancer, bacterial, fungal, and parasitic infections, or neurodegenerative diseases, as well as their applications in immunotherapy, diagnostic imaging, and radiopharmaceuticals. Additional areas of interest include chelation strategies for metal overload disorders, detoxification, and heavy metal poisoning. We also welcome computational studies and applied investigations into pharmacokinetics and bioavailability.

We look forward to your contributions and are confident that this collection will serve as a valuable resource for the scientific community.

Dr. Matteo Mori
Dr. Fiorella Meneghetti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metal complexes
  • chelation therapy
  • chelating agents
  • diagnostic imaging
  • metal detoxification
  • chelation pharmacokinetics

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Published Papers

This special issue is now open for submission.
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