Diabetes: Genetics and Genomics, Hormone Regulation, and Metabolic Control
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 March 2025 | Viewed by 74
Special Issue Editor
Interests: epigenetics; non-coding RNAs; genome-wide association study; GWAS; EWAS; genetic variability; epidemiology; nutrition
Special Issue Information
Dear Colleagues,
Diabetes is a heterogeneous disease with different types, which are influenced by a complex array of genetic and genomic factors that shape their development, progression, and response to treatment. Advances in genomics have opened new avenues for understanding the hereditary aspects of these conditions, from monogenic forms of diabetes to the more intricate polygenic risk factors associated with the different types of diabetes. The integration of genetics with endocrinology has also shed light on the molecular mechanisms governing hormone regulation and metabolic balance, offering new perspectives on disease pathophysiology.
This Special Issue will highlight cutting-edge research and reviews on genetic and genomic contributions to diabetes. We invite submissions addressing (1) genetic variations and their role in diabetes susceptibility; (2) the genomics of insulin production, hormone action, and metabolic regulation; (3) epigenetic modifications influencing disease progression; (4) interactions between genetic predispositions and environmental factors; and (5) applications of genomic data for precision medicine approaches in diabetes. Through these contributions, we aim to advance the understanding of how genetics and genomics drive disease outcomes, intending to improve diagnostics, treatment, and prevention strategies.
Dr. Maria Stathopoulou
Guest Editor
Manuscript Submission Information
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Keywords
- type 1 diabetes
- type 2 diabetes
- monogenic diabetes
- polygenic risk factors
- gestational diabetes (GDM)
- maturity-onset diabetes of the young (MODY)
- latent autoimmune diabetes in adults (LADAs)
- genome-wide association studies (GWASs)
- single nucleotide polymorphisms (SNPs)
- epigenetic modifications in diabetes
- insulin production regulation
- hormone action and metabolic control
- β-cell dysfunction
- gene-environment interactions in diabetes
- precision medicine in diabetes treatment
- genetics
- genomics
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