Molecular Research on Neuroprotection: the State-of-the Art
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (30 April 2023)
Special Issue Editor
Interests: isatin; isatin metabolism; isatin analogues; isatin-based pharmacological agents; isatin binding proteins; neuroprotection; molecular mechanisms; ligand-receptor interaction; isatin-responsive genes; proteomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleague,
Neuroprotection is an approach that helps organisms to defend their neurons against various pathological factors of different origin and to prevent neuronal cell death by attenuating/inhibiting pathogenetic cascades responsible for nerve cell dysfunction. Various endogenous and exogenous factors, which act at numerous cellular targets, may potentially delay progressive neurodegeneration. The protection of nerve cells against various damaging factors is in the constant focus of many scientists worldwide. A simple search in Pubmed shows that every year, several thousands of papers are published on various aspects of neuroprotection. This means that despite recent excellent issues on related subjects published by MDPI and other journals, there is a clear need for an evaluation of the current state of the art in this field.
I cordially invite researchers to submit original papers and comprehensive reviews, describing results of recent studies that are in the context of existing knowledge on molecular mechanisms of neuroprotection. Characterizations of “old” and newly discovered biological targets for the action of neuroprotective agents are welcomed. It would be particularly interesting to evaluate the biological activity of newly synthesized small molecules and/or traditional folk medicine ingredients and their role as potential neuroprotectors in cell and animals models.
Dr. Alexei E. Medvedev
Guest Editor
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Keywords
- neuroprotection
- neurodegeneration
- neuroprotectors
- molecular mechanisms
- signaling pathways
- small molecule inhibitors
- biological targets
- cell and animal models
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