Mechanisms Regulating Osteoclastogenesis in Physiological and Pathological Conditions
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (31 May 2018)
Special Issue Editors
Interests: osteoimmunology; osteoclast; osteoblast; bone remodeling; bone diseases; cardiovascular disease
Special Issues, Collections and Topics in MDPI journals
Interests: stem cells; osteoclast; osteoblast; bone remodeling; tissue regeneration
Special Issues, Collections and Topics in MDPI journals
Interests: bone health; nutrigenomics; nutraceuticals; polyphenols; extra virgin olive oil
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
Bone remodeling is a tightly regulated process involving the interplay among osteoclasts, osteoblasts, and osteocytes. Osteoclasts are the bone resorbing cells arising from the fusion of monocyte/macrophage precursors. Osteoclastogenesis is primarily supported by osteoblasts but also by other cells of the bone marrow microenvironment, such as immune cells, adipocytes, and endothelial cells. Osteoclastogenesis is a finely controlled process, and its deregulation is related to different bone diseases; thus, the deepening of the mechanisms regulating osteoclast formation can be useful for identifying new pharmacological targets.
The Editors encourage submissions of full-review or original research papers, and perspectives on the biological, functional, and mechanistic question(s) being addressed.
Prof. Giacomina Brunetti
Prof. Giorgio Mori
Prof. Maria Felicia Faienza
Guest Editors
Manuscript Submission Information
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Keywords
- osteoclasts
- osteoimmunology
- T cells
- B cells
- bone marrow microenvironment
- osteoblasts
- growth factors
- cytokines
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