Calcium-Binding Proteins and Cell Signaling, 4th Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 April 2025 | Viewed by 302
Special Issue Editor
Interests: calcium-binding protein; membrane traffic
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Calcium ions play pivotal roles in a variety of cellular events, including signal transduction, gene expression, cell death, fertilization, muscle contraction, membrane fusion, blood clotting, enzymatic activations of kinases, phosphatases, proteases, etc., by involving different kinds of calcium-binding proteins. The concentrations of Ca2+ in the blood and inside cells are strictly regulated by Ca2+-sensing proteins, channels, and transporters and Ca2+-buffering proteins. In addition to the sarcoplasmic/endoplasmic reticulum, known as the major Ca2+-storage organelle in the cell, mitochondria, Golgi apparatus, endosomes, and lysosomes are also known to play roles in Ca2+ signaling. The nuclear roles of Ca2+ in transcriptional and post-transcriptional regulation are also drawing attention. Ca2+ works not only as a second messenger but also as a first messenger for Ca2+-sensing receptors located on the plasma membrane. Abnormalities in Ca2+ homeostasis or in the functions of Ca2+-regulated factors cause, directly or indirectly, various diseases, such as neuropathies, heart failure, immune disorders, and osteogenesis imperfecta. Ca2+-dependent phenomena are not restricted to animals; plants, lower eukaryotes, and some bacteria also use Ca2+ as a signaling molecule.
As volumes 1, 2, and 3 of Special Issues “Calcium-Binding Proteins and Cell Signaling” are successful, we reopen this issue again in the International Journal of Molecular Sciences (https://www.mdpi.com/journal/ijms, ISSN 1422-0067, IF 5.924, JCR Category Q1). This forth Special Issue, “Calcium-Binding Proteins and Cell Signaling, 4th Edition”, welcomes contributions covering all areas of basic and application-oriented research associated with calcium regarding the aspects of biochemistry, cell biology, molecular biology, and biophysics.
Dr. Hideki Shibata
Guest Editor
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Related Special Issues
- Calcium-Binding Proteins and Cell Signaling in International Journal of Molecular Sciences (9 articles)
- Calcium-Binding Proteins and Cell Signaling 2.0 in International Journal of Molecular Sciences (18 articles)
- Calcium-Binding Proteins and Cell Signaling 3.0 in International Journal of Molecular Sciences (28 articles)
