The Role of the IGF Axis in Disease, 4th Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 28 February 2025 | Viewed by 362
Special Issue Editor
Interests: metabolic disturbances; IGFs and epithelial cancers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue continues on from our previous Special Issues, "The Role of the IGF Axis in Disease", “The Role of the IGF Axis in Disease 2.0”, and “The Role of the IGF Axis in Disease, 3nd Edition”.
This research topic aims to highlight the key roles that members of the insulin-like growth factor (IGF) axis (including ligands, IGF-I and -II, IGF binding proteins (IGFBPs1-6) and IGF receptors) play in the risk and development of diseases. The IGF family can affect many physiological systems in the body by modulating cell processes, including proliferation, differentiation, survival, and metabolism. Consequently, they are often dysregulated in many pathological conditions, leading to the development of different strategies to target them.
Dr. Claire M. Perks
Guest Editor
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Keywords
- IGF axis
- cancer
- obesity
- hallmarks of cancer
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