Molecular Mechanism and Pathogenesis of Cardiac Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 195
Special Issue Editor
Interests: cellular metabolism in cardiac pathophysiology; epigenetic regulation of cardiac pathophysiology; regulation of cardiac fibrosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The understanding of cardiac diseases has significantly advanced with the identification of the molecular regulatory processes underlying their pathophysiology. Epigenetic mechanisms, including non-coding RNA, histone modification, and DNA methylation, play pivotal roles in connecting genetic predispositions with environmental influences in order to modulate gene expression and protein functions in cardiac diseases. Additionally, ER stress and inflammasomes contribute to the inflammatory processes that drive the onset and progression of cardiac diseases. Mitochondria, as essential regulators of cardiac metabolism, biosynthesis, redox balance, calcium homeostasis, and cell death, are a key area of interest for investigating the molecular signaling pathways leading to mitochondrial dysfunction.
In recent years, significant progress has been made in developing therapeutic strategies aimed at targeting these molecular pathways. Advances in drug development, gene therapy, and precision medicine offer promising avenues for improving the treatment and management of cardiac diseases.
The Special Issue, entitled “Molecular Mechanism and Pathogenesis of Cardiac Disease”, aims to provide a comprehensive research platform for the latest original and review articles. We invite contributions that explore molecular biological studies related to the regulation of cardiac diseases, elucidate the mechanisms of therapeutic drugs, and present advancements in treatment strategies designed to enhance cardiac health outcomes.
Dr. Yu-Hsun Kao
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- cardiac diseases
- cardiac metabolidm
- epigenetics
- ER stress
- mitochondrial dysfunction
- molecular mechanisms
- therapeutic targets
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