Coumarins as Effective Therapeutic Agents: Mechanism of Action and Diverse Activity
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 290
Special Issue Editor
Interests: furanocoumarins; pyranocoumarins; simple coumarins; anti-inflammatory properties; cytotoxic activity; antitumor activity; antimicrobial acitivity; bioactivity of compounds; anxiolytic activity; neuroprotective properties; bioactive metabolites; medicinal plants
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Special Issue Information
Dear Colleagues,
Coumarins are heterocyclic compounds belonging to the class of benzopyrenes, found in various plants, fungi and microorganisms. Coumarins and their derivatives show great chemical diversity and include furanocoumarins, pyranocoumarins, as well as simple coumarins. These natural compounds exhibit bioactive properties such as anticoagulant, antimicrobial, anti-inflammatory, antioxidant, antimalarial, anticancer, antiviral and enzyme inhibitory effects, including acetylcholinesterase, COX or tyrosinase. In recent years, there has been an increasing number of reports on the activity of coumarins in the central nervous system, and they have exhibited neuroprotective, anticonvulsant and anti-anxiety effects.
This Special Issue will include a selection of articles highlighting the current challenges in phytochemical research on coumarins and determining their pharmacological activity and possible applications.
The theme of the issue will be innovative approaches to understanding the molecular mechanisms underlying the pharmacological activity of coumarins, which can be used in the treatment and prevention of many diseases. We invite you to participate in this Special Issue by submitting original research, short communications and review manuscripts. This is a great opportunity to contribute to the search for new natural medicines.
Dr. Jarosław Widelski
Guest Editor
Manuscript Submission Information
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Keywords
- furanocoumarins
- pyranocoumarins
- simple coumarins
- anti-inflammatory properties
- cytotoxic activity
- antitumor activity
- antimicrobial acitivity
- bioactivity of compounds
- anxiolytic activity
- neuroprotective properties
- bioactive metabolites
- medicinal plants
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