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How Should We Assess Stenosis for Revascularization: Fractional Flow Reserve...
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How Should We Assess Stenosis for Revascularization: Fractional Flow Reserve (FFR) Versus Intravascular Ultrasound (IVUS)

A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425). This special issue belongs to the section "Imaging".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1239

Special Issue Editor

Dr. Indrė Čeponienė

E-Mail Website
Guest Editor
Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, 44307 Kaunas, Lithuania
Interests: coronary atherosclerosis; coronary plaque; vulnerable plaque; plaque imaging

Special Issue Information

Dear Colleagues,

The Journal of Cardiovascular Development and Disease is planning to host a Special Issue that will focus on the invasive assessment of coronary artery stenosis and the role of fractional flow reserve (FFR) and intravascular ultrasound (IVUS) in the decision-making process regarding further coronary artery disease management. Coronary angiography has been a gold standard for stenosis assessment for many years; however, extensive amounts of the literature data suggest that a visual assessment of stenosis is not enough. The presence of ischemia defined by the value of FFR (or iFR, QFR) and plaque characteristics visualized with IVUS play an important role in the decision-making process. However, it is unclear which modality, FFR or IVUS, better predicts clinical outcomes. In this Special Issue, we invite you to submit research papers or review articles exploring any aspects related to this topic, including comparison between IVUS and FFR modalities such as iFR and QFR, and the role of invasive imaging in non-obstructive coronary artery disease.

Dr. Indrė Čeponienė
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fractional flow reserve
  • invasive plaque assessment
  • intravascular ultrasound
  • revascularization

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Published Papers (1 paper)

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Research

11 pages, 655 KiB  
Article
Impact of Chronic Kidney Disease on the Coronary Revascularization Guided by Intracoronary Physiology: Results of the First Registry with Long-Term Follow-Up in a Latin American Population
by Clarissa Campo Dall’Orto, Rubens Pierry Ferreira Lopes, Lara Vilela Eurípedes, Gilvan Vilella Pinto Filho and Marcos Raphael da Silva
J. Cardiovasc. Dev. Dis. 2024, 11(7), 216; https://doi.org/10.3390/jcdd11070216 - 10 Jul 2024
Viewed by 794
Abstract
The use of invasive physiology methods in patients with renal dysfunction is not well elucidated. Our objective was to evaluate the in-hospital and long-term results of using intracoronary physiology to guide revascularization in patients with chronic kidney disease. In this retrospective study, we [...] Read more.
The use of invasive physiology methods in patients with renal dysfunction is not well elucidated. Our objective was to evaluate the in-hospital and long-term results of using intracoronary physiology to guide revascularization in patients with chronic kidney disease. In this retrospective study, we evaluated 151 patients from January 2018 to January 2022, divided into 2 groups: CKD (81 patients [114 lesions]) and non-CKD (70 patients [117 lesions]). The mean age was higher (p < 0.001), body mass index was lower (p = 0.007), contrast volume used was lower (p = 0.02) and the number of ischemic lesions/patients was higher (p = 0.005) in the CKD group. The primary outcomes (rate of major adverse cardiac events during follow-up, defined as death, infarction, and need for new revascularization) in the CKD and non-CKD groups were 22.07% and 14.92%, respectively (p = 0.363). There was a significant difference in the target lesion revascularization (TLR) rate (11.68%, CKD group vs. 1.49%, non-CKD group, p = 0.02), this initial statistical difference was not significant after adjusting for variables in the logistic regression model. There was no difference between the rates of death from all causes (6.49%, CKD group vs. 1.49%, non-CKD group, p = 0.15), reinfarction (3.89%, CKD group vs. 1.49%, non-CKD group, p = 0.394), and need for new revascularization (11.68%, CKD group vs. 5.97%, non-CKD group, p = 0.297). As there was no difference in the endpoints between groups with long-term follow-up, this study demonstrated the safety of using intracoronary physiology to guide revascularization in patients with CKD. Full article
(This article belongs to the Special Issue How Should We Assess Stenosis for Revascularization: Fractional Flow Reserve (FFR) Versus Intravascular Ultrasound (IVUS))
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