Established and Novel Approaches for Sarcopenia: Second Edition
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Rehabilitation".
Deadline for manuscript submissions: 20 April 2025 | Viewed by 1228
Special Issue Editor
Interests: skeletal and cardiac muscle physiology; exercise physiology; clinical exercise physiology; molecular exercise physiology; mechanotransduction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
We are pleased to announce the second edition of this Special Issue, “Established and Novel Approaches for Sarcopenia” (https://www.mdpi.com/journal/jcm/special_issues/9XI27I935X).
Sarcopenia represents the progressive age-related wasting of skeletal muscle mass accompanied by the loss of muscle strength. A decline in muscle strength and function is associated with an increased risk of adverse health outcomes, and sarcopenia patients are faced with mobility disorders, disability, a loss of independence, and reduced quality of life, while they are at a higher risk for morbidity (e.g., falls, bone fractures, and metabolic diseases, as skeletal muscle is one of the most important tissues for metabolic control) and mortality. Considering the growing elderly population and the increasing life expectancy, the prevalence of sarcopenia will escalate in the upcoming years. This provides the rationale for further characterizing the molecular mechanisms and abnormalities of sarcopenia, including abnormal energy metabolism, mitochondrial dysfunction, and myofiber type transition, as the basis for revealing and effectively treating its risk factors, thus developing efficient preventive and therapeutic strategies. Herein, we set up a Special Issue to incorporate papers focusing on established and novel approaches for sarcopenia, including, but not limited to, nutrition supplementation, pharmacological approaches, and physical exercise as interventions for sarcopenia. The Special Issue aims to present established, advanced, and novel insights for preventing or treating sarcopenia to decrease its comorbidities, and hence improve quality of life, increase life expectancy, and limit healthcare costs for these patients.
Dr. Anastassios Philippou
Guest Editor
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Keywords
- sarcopenia
- skeletal muscle wasting
- muscle atrophy
- myopathy
- muscle protein catabolism
- abnormal energy metabolism
- mitochondrial dysfunction
- myofiber type transition
- morbidity
- treatment strategies
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