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Clinical Advances in Neurosurgery
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Clinical Advances in Neurosurgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: closed (1 August 2024) | Viewed by 2894

Special Issue Editor

Dr. Peter G. Passias

E-Mail Website
Guest Editor
Division of Spinal Surgery, Department of Neurological and Orthopaedic Surgery, NYU Langone Medical Center, NYU School of Medicine 550 1st Ave., New York, NY 10016, USA
Interests: orthopaedic surgery; lordosis; kyphosis; spinal cord diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The field of neurological surgery has seen tremendous growth in recent years, whether this be through technical advances in operative techniques or novel treatment methods. As a result, patients, surgeons, and healthcare systems have seen improving clinical and patient-reported outcomes in addition to reduced morbidity or mortality in many subsects of the specialty. Yet, the complexity of both patient populations and treatments continues to increase. Research on the impact of clinical advances in neurosurgery remains at the forefront of importance to ensure that treatments are clinically and economically efficacious. In this Special Issue, we invite authors to submit works focusing on assessments of clinical advances in neurosurgery, including, but not limited to, emerging diagnostic modalities, deep brain stimulation (DBS), stereotactic radiosurgery (SRS), spinal surgery, and complication management to better understand impacts within a rapidly evolving surgical specialty. 

Dr. Peter G. Passias
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neurosurgery
  • neurological surgery
  • clinical advances
  • complications
  • spine surgery
  • deep brain stimulation (DBS)
  • stereotactic radiosurgery (SRS)
  • movement disorders
  • peripheral nerve disorders
  • minimally invasive neurosurgery

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Published Papers (2 papers)

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Research

12 pages, 14589 KiB  
Article
Endoscopic Lumbar Disc Surgery Experience with the TESSYS Technique in 253 Case Series
by Aldo Spallone, Roman Vladimirovich Khalepa, Evgeniya Amelina and Amrakh Magerramov Asif ogly
J. Clin. Med. 2024, 13(7), 1911; https://doi.org/10.3390/jcm13071911 - 26 Mar 2024
Viewed by 978
Abstract
Background: Herniated lumbar disc (HLD) is a widespread medical problem which can require surgery. Minimally invasive surgical management can represent an extremely valuable option for patients suffering from HLDs. Transforaminal endoscopic lumbar discectomy is an alternative to classical microdiscectomy which was proposed [...] Read more.
Background: Herniated lumbar disc (HLD) is a widespread medical problem which can require surgery. Minimally invasive surgical management can represent an extremely valuable option for patients suffering from HLDs. Transforaminal endoscopic lumbar discectomy is an alternative to classical microdiscectomy which was proposed more than two decades ago and has evolved technologically with time. Methods: The transforaminal endoscopic spine system (TESSYS) technique has been introduced in recent years and offers the advantage of performing a controlled foraminal augmentation with full nerve root protection. We started using this technique in 2016 and prospectively evaluated the results of endoscopic TESSYS-based operations performed in a three-year period until the end of 2019. Selection criteria were very strict, and we included only patients with unilateral radicular pain with no instability who failed conservative therapy. Out of the 253 patients operated on in that time span, 183 were available for follow-up evaluation. Results: After surgery, there was a clinically significant improvement of all symptoms which basically lasted in the long-term follow-up. Complications were limited and generally minor. Redo surgery with microdiscectomy was required only in four cases. Obesity did not play a clear negative role in patients’ outcome. Conclusions: Endoscopic transforaminal discectomy with the TESSYS technique represents a valuable management option for patients harbouring unilateral herniated lumbar disc located laterally. Full article
(This article belongs to the Special Issue Clinical Advances in Neurosurgery)
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14 pages, 7555 KiB  
Article
Recipient Reaction and Composition of Autologous Sural Nerve Tissue Grafts into the Human Brain
by Isaac Colvett, Anah Gilmore, Samuel Guzman, Aurélie Ledreux, Jorge E. Quintero, Dhanunjaya Rao Ginjupally, Julie A. Gurwell, John T. Slevin, Zain Guduru, Greg A. Gerhardt, Craig G. van Horne and Ann-Charlotte Granholm
J. Clin. Med. 2023, 12(19), 6121; https://doi.org/10.3390/jcm12196121 - 22 Sep 2023
Cited by 1 | Viewed by 1409
Abstract
Parkinson’s disease (PD) is a severe neurological disease for which there is no effective treatment or cure, and therefore it remains an unmet need in medicine. We present data from four participants who received autologous transplantation of small pieces of sural nerve tissue [...] Read more.
Parkinson’s disease (PD) is a severe neurological disease for which there is no effective treatment or cure, and therefore it remains an unmet need in medicine. We present data from four participants who received autologous transplantation of small pieces of sural nerve tissue into either the basal forebrain containing the nucleus basalis of Meynert (NBM) or the midbrain substantia nigra (SN). The grafts did not exhibit significant cell death or severe host-tissue reaction up to 55 months post-grafting and contained peripheral cells. Dopaminergic neurites showed active growth in the graft area and into the graft in the SN graft, and cholinergic neurites were abundant near the graft in the NBM. These results provide a histological basis for changes in clinical features after autologous peripheral nerve tissue grafting into the NBM or SN in PD. Full article
(This article belongs to the Special Issue Clinical Advances in Neurosurgery)
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