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Diabetic Foot and Other Complications of Diabetes: Clinical Management and...
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Diabetic Foot and Other Complications of Diabetes: Clinical Management and Prevention

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Endocrinology & Metabolism".

Deadline for manuscript submissions: closed (25 September 2024) | Viewed by 3021

Special Issue Editors

Dr. Raúl J. Molines Barroso

E-Mail Website
Guest Editor
1. Diabetic Foot Unit, Facultad de Enfermería, Fisioterapia y Podología, Universidad Complutense de Madrid, 28040 Madrid, Spain
2. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain
Interests: diabetic foot; diabetic foot ulcers; diabetic foot prevention; diabetic foot ostemyelitis; biomechanics; charcot foot
Dr. Irene Sanz-Corbalan

E-Mail Website
Guest Editor
1. Diabetic Foot Unit, Faculty of Nursing, Physiotherapy, and Podiatry, Complutense University of Madrid, 28040 Madrid, Spain
2. Health Research Institute of the San Carlos Clinical Hospital (IdISSC), 28040 Madrid, Spain
Interests: diabetic foot; diabetic foot osteomyelitis; diabetic neuropathy; diabetic foot care

Special Issue Information

Dear Colleagues,

In spite of the recent advancements achieved in the diagnosis and treatment of diabetes, the disease is still considered a global epidemic, and the effects of diabetic foot and other complications contribute to worse survival rates than common cancers such us prostate or breast cancer. In addition, these complications are a leading cause of disability and decreased quality of life; however, these outcomes are readily preventable with evidence-based disease care. In this Special Issue, we hope to compile up-to-date articles and reviews on aspects of the diabetic foot and other complications of diabetes, ranging from a multidisciplinary approach to the prevention and management of these serious complications.

Dr. Raúl J. Molines Barroso
Dr. Irene Sanz-Corbalan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • diabetic foot
  • prevention
  • epidemiology
  • pathogenesis
  • complications
  • polineuropathy
  • neuropathic pain
  • vascular disease
  • charcot foot
  • diabetic foot infections
  • treatment strategies

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Published Papers (2 papers)

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Research

12 pages, 248 KiB  
Article
Osteoporosis as the Female-Specific Risk Factor for Dynapenia in Elderly Patients with Type 2 Diabetes
by Chieh-Hua Lu, Sheng-Chiang Su and Feng-Chih Kuo
J. Clin. Med. 2024, 13(16), 4590; https://doi.org/10.3390/jcm13164590 - 6 Aug 2024
Viewed by 798
Abstract
Aims: Dynapenia is a noteworthy health issue contributing to increased risk of falling, but its co-occurrence with osteoporosis in elderly individuals with type 2 diabetes mellitus (T2DM) has not been well explored. Therefore, this study aimed to establish the association between osteoporosis and [...] Read more.
Aims: Dynapenia is a noteworthy health issue contributing to increased risk of falling, but its co-occurrence with osteoporosis in elderly individuals with type 2 diabetes mellitus (T2DM) has not been well explored. Therefore, this study aimed to establish the association between osteoporosis and dynapenia, focusing on T2DM females due to their high prevalence of osteoporosis and fragility. Methods: We conducted a cross-sectional study to recruit a total of 103 T2DM patients (43 males and 60 females), aged between 50 and 80 years with median 68.0 years. Dual-energy X-ray absorptiometry (DXA) and dominant hand grip strength measurements were performed to define body composition, osteoporosis, and dynapenia in a sex-specific manner. Results: Higher prevalence of dynapenia and dyna-osteoporosis was observed in female T2DM patients with a significantly positive correlation between osteoporosis and dynapenia even after adjustment of body mass index (BMI). By performing a multivariate logistic regression analysis, both BMI and osteoporosis were identified as risk predictors for the development of dynapenia in female T2DM patients with odds ratios (95% CIs) of 1.234 (1.029–1.480) and 4.883 (1.352–17.630), respectively. Conclusions: Our results point out there is high, female-specific co-occurrence of osteoporosis and dynapenia in T2DM patients. Moreover, having osteoporosis and increased BMI might boost the risk of dynapenia in elderly females with T2DM. Full article
(This article belongs to the Special Issue Diabetic Foot and Other Complications of Diabetes: Clinical Management and Prevention)
10 pages, 557 KiB  
Article
Intra-Observer and Inter-Observer Reliability of Ankle Circumference Measurement in Patients with Diabetic Foot: A Prospective Observational Study
by David Montoro-Cremades, Aroa Tardáguila-García, David Navarro-Pérez, Yolanda García-Álvarez, Mateo López-Moral and José Luis Lázaro-Martínez
J. Clin. Med. 2023, 12(22), 7166; https://doi.org/10.3390/jcm12227166 - 18 Nov 2023
Viewed by 1779
Abstract
Inflammation, being a typical response to vascular tissue alterations, induces variations in tissue oxygen diffusion pressure. Diabetic microangiopathy, an inflammatory process, is characterized by an increase in vascular flow at rest, reduced venous and arteriolar responses, and increased capillary permeability, resulting in oedema [...] Read more.
Inflammation, being a typical response to vascular tissue alterations, induces variations in tissue oxygen diffusion pressure. Diabetic microangiopathy, an inflammatory process, is characterized by an increase in vascular flow at rest, reduced venous and arteriolar responses, and increased capillary permeability, resulting in oedema development, decreased transcutaneous oxygen pressure, and increased transcutaneous carbon dioxide pressure. This phenomenon potentially hampers ulcer healing. Although the figure-of-eight method has proven to be a reliable, valid, quick, and efficient test for assessing foot and ankle measurements in patients with oedema and compromised skin integrity, it has not been studied in patients with diabetic foot. The aim of this study was to determine and compare the intra- and inter-observer variabilities of the figure-of-eight method in patients with diabetic foot. A prospective observational and cross-sectional study was undertaken, involving sixty-one subjects from a specialized Diabetic Foot Unit. Three investigators with varying levels of experience independently measured the subjects to assess both intra-observer and inter-observer variability. The evaluation was conducted using the Intraclass Correlation Coefficient (ICC). In the statistical analysis, an ICC of 0.93, adjusted using a 95% confidence interval (CI), was obtained for inter-observer reliability ICC, indicating excellent reliability among observers. Furthermore, an ICC of 0.98 with a 95% CI was obtained for the intra-observer reliability analysis, indicating excellent reliability. The results support using this test during the clinical management of oedema in patients with diabetic foot. The absence of an objective, fast, and readily available diagnostic method for oedema in diabetic foot patients in clinical practice might pose a limitation. Subsequent research should tackle this issue and explore the correlation between ankle perimeter measurements and other clinical outcomes in diabetic foot patients, including wound healing and quality of life. Full article
(This article belongs to the Special Issue Diabetic Foot and Other Complications of Diabetes: Clinical Management and Prevention)
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