New Insights in the Endovascular Treatment of Aortic Type A Dissection

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 2251

Special Issue Editor


E-Mail Website
Guest Editor
Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin, Berlin, Germany
Interests: minimally invasive mitral valve surgery; outcomes following mitral valve repair; transcatheter valve therapy; pathophysiology of mitral valve disease; genetics

Special Issue Information

Dear Colleagues,

Acute type A aortic dissection represents a formidable challenge in cardiothoracic surgery, necessitating urgent intervention to mitigate catastrophic complications. While open surgical repair still represents the gold standard, hybrid and endovascular techniques have emerged as promising alternatives and may have the potential to offer reduced morbidity and mortality rates. However, stent-driven therapies are not yet integrated into clinical routines and are primarily conducted at specialized aortic centers. Many different factors contribute to the high complexity of hybrid and endovascular therapeutic approaches, which could represent an attractive alternative, especially for critically ill patients.

Substantial knowledge and treatment gaps persist that must be addressed in order to facilitate these approaches in the treatment of acute type A aortic dissection and improve patient care. This Special Issue focuses on advancements and novel insights in hybrid and endovascular management of acute type A aortic dissection, elucidating key considerations in patient selection, procedural techniques, and outcome assessment.

Let's work together and collectively take a stride toward bridging the treatment gap for hybrid and endovascular approaches to managing acute type A aortic dissection—for the community and our patients.

Dr. Markus Kofler
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • aortic dissection
  • endovascular treatment
  • type A dissection
  • thoracic aorta
  • stent graft
  • minimally invasive surgery
  • hybrid procedures
  • complications
  • long-term outcomes
  • patient selection

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Jump to: Review

12 pages, 2509 KiB  
Article
A Meta-Analysis of Timing of Complete Revascularization in Patients with ST-Elevation Myocardial Infarction
by Michał Kuzemczak, Abdelrahman Mahmoud, Mohammed A. R. Abdellatif and Mohammad Alkhalil
J. Clin. Med. 2024, 13(23), 7107; https://doi.org/10.3390/jcm13237107 - 24 Nov 2024
Viewed by 872
Abstract
Background: Recent randomized clinical trials (RCTs) of STEMI patients with multi-vessel disease (MVD) reported potential superiority of immediate (ICR) vs. staged complete revascularization (SCR). Inherently, the risk of procedural MI is less likely to be detected in ICR patients, and this may [...] Read more.
Background: Recent randomized clinical trials (RCTs) of STEMI patients with multi-vessel disease (MVD) reported potential superiority of immediate (ICR) vs. staged complete revascularization (SCR). Inherently, the risk of procedural MI is less likely to be detected in ICR patients, and this may have influenced the results. Recently published meta-analyses encompassed observational studies without including STEMI data from the BioVasc trial. The aim of this meta-analysis was to perform an updated comparison of the two strategies in STEMI patients with MVD. Methods: Electronic databases were searched from their inception till August 2024 to identify RCTs assessing CR timing in STEMI patients with MVD. Only studies with an endpoint involving major adverse cardiovascular events (MACE) were included. Results: Six RCTs totaling 2023 patients were included in the analysis. The median time to staged PCI was 19 days. The incidence of MACE (as defined by each study’s protocol) was comparable between the two strategies [RR 0.86, 95% CI (0.58 to 1.27)]. There was also no difference in the risk of non-procedural MI [RR 0.91, 95% CI (0.49–1.67)], death [RR 1.47, 95% CI (0.89–2.44)] and cardiovascular death [RR 1.53, 95% CI (0.79–2.98)]. There was a significant 40% reduction in unplanned revascularization in patients undergoing ICR versus SCR [RR 0.60 (0.40 to 0.89), p = 0.01]. Conclusions: ICR reduced the risk of unplanned revascularization compared to SCR but had a comparable effect on MACE, death, cardiovascular death and non-procedural MI. Both strategies are safe in managing patients with acute MI and MVD. Full article
Show Figures

Figure 1

Review

Jump to: Research

14 pages, 623 KiB  
Review
The Unique Challenge of Coronary Artery Disease in Adult Patients with Congenital Heart Disease
by Nunzia Borrelli, Assunta Merola, Rosaria Barracano, Michela Palma, Ippolita Altobelli, Massimiliana Abbate, Giovanni Papaccioli, Giovanni Domenico Ciriello, Carmen Liguori, Davide Sorice, Lorenzo De Luca, Giancarlo Scognamiglio and Berardo Sarubbi
J. Clin. Med. 2024, 13(22), 6839; https://doi.org/10.3390/jcm13226839 - 14 Nov 2024
Viewed by 964
Abstract
Advances in medical and surgical interventions have resulted in a steady increase in the number of patients with congenital heart disease (CHD) reaching adult age. Unfortunately, this ever-growing population faces an added challenge: an increased risk of acquiring coronary artery disease. This review [...] Read more.
Advances in medical and surgical interventions have resulted in a steady increase in the number of patients with congenital heart disease (CHD) reaching adult age. Unfortunately, this ever-growing population faces an added challenge: an increased risk of acquiring coronary artery disease. This review provides insight into the complex interactions between coronary artery disease and CHD in adults. We describe the peculiar features of cardiac anatomy in these patients, the possible role cardiac sequelae may play in an increased risk of myocardial ischemia, and the diagnostic challenges in this patient group. Furthermore, this review outlines the risk factors and potential mechanisms of accelerated atherosclerosis in adults with CHD by pointing out areas where current knowledge is incomplete and highlighting areas for further research. The review concludes by examining potential management strategies for this particular population, emphasizing the necessity for a multidisciplinary approach. Understanding the unique coronary risks that adults with CHD experience can enhance patient care and improve long-term results. Full article
Show Figures

Figure 1

Back to TopTop