Traumatic Brain Injury: Emergency Management, Prevention of Secondary Injury, and Rehabilitation

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Brain Injury".

Deadline for manuscript submissions: 20 February 2025 | Viewed by 2883

Special Issue Editors


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Guest Editor
Department of Neurology, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, 811 Kaufmann Medical Building, 3471 Firth Avenue, Pittsburgh, PA 15213, USA
Interests: cerebral edema; traumatic brain injury; hemorrhagic stroke; intracerebral hemorrhage; neurointensive care

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Guest Editor
Department of Neurology, University of Leipzig, Liebigstrasse 20, 04103 Leipzig, Germany
Interests: neuroemergencies; glucose control after stroke; traumatic brain injury; subarachnoid hemorrhage; neurocritical care

Special Issue Information

Dear Colleagues,

Traumatic brain injury (TBI) continues to be one of the top three leading causes of death and severe disability worldwide, which poses an enormous burden on families, caregivers, and the economy and health care systems. With the constantly aging population, especially in high-income countries, the incidence of falls resulting in TBI is expected to rise.

Improvements in emergency management, diagnostic tools, and neurocritical care, with special attention to secondary injuries and their differential diagnosis and neuromonitoring, as well as rehabilitation programs, have contributed to a better understanding of individual pathophysiology and outcomes after TBI. Multidimensional outcome assessment tools have been developed.

Clinicians and scientists are encouraged to submit original research papers or state-of-the-art reviews for this upcoming Special Issue focusing on aspects of acute management and neurocritical care of TBI patients, neuromonitoring, rehabilitation during the acute, subacute, and chronic phases, as well as outcome assessment after a TBI.

Dr. Katja E. Wartenberg
Prof. Dr. Lori Shutter
Guest Editors

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Keywords

  • traumatic brain injury
  • neuromonitoring
  • neurocritical care
  • neurorehabilitation
  • secondary injury
  • outcome
  • prognostication

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Published Papers (1 paper)

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11 pages, 623 KiB  
Commentary
Albumin in Normovolemic Fluid Management for Severe Traumatic Brain Injury: Controversies and Research Gaps
by Christian J. Wiedermann
J. Clin. Med. 2024, 13(18), 5452; https://doi.org/10.3390/jcm13185452 - 13 Sep 2024
Viewed by 2579
Abstract
Traumatic brain injury (TBI) is a significant public health issue characterized by high mortality rates and long-term complications. This commentary examines the controversial role of the use of albumin in the fluid management of patients with severe TBI. Despite its physiological benefits, the [...] Read more.
Traumatic brain injury (TBI) is a significant public health issue characterized by high mortality rates and long-term complications. This commentary examines the controversial role of the use of albumin in the fluid management of patients with severe TBI. Despite its physiological benefits, the clinical use of albumin remains controversial due to the fact that various studies have yielded mixed results. Serum albumin is important for maintaining normovolemia, primarily through its contribution to colloid osmotic pressure, which helps to retain fluid in the circulatory system. This review highlights the existing evidence, examines inconsistencies in guideline recommendations, and suggests future research directions to clarify the efficacy and safety of the use of albumin in maintaining normovolemia in patients with TBI. The review also discusses the potential benefits of small-volume resuscitation strategies for the management of acute kidney injury in TBI patients, drawing parallels with the management of septic acute kidney injury. The need for further well-designed randomized controlled trials and ethical considerations in studies regarding the use of hyperoncotic albumin in TBI management is emphasized. Full article
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