New Advances in Cardiorenal Syndrome: 2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1403

Special Issue Editor


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Guest Editor
1. Dept Internal Med II, Martin Luther UniversityHalle Wittenberg, 06108 Halle, Germany
2. Dept Nephrol and Diabetol, Carl Thiem Hospital, 03048 Cottbus, Germany
Interests: cardiology; heart failure; hypertension; diabetes mellitus; chronic heart failure; blood pressure; atherosclerosis; chronic kidney disease
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Special Issue Information

Dear colleagues,

As the Guest Editor, it is my privilege to invite you to discover new and relevant research results on cardiorenal syndrome in the upcoming second edition of our Special Issue titled “Advances in Cardiorenal Syndrome” (https://www.mdpi.com/journal/jcm/special_issues/Advances_Cardiorenal_Syndrome). The new collection will cover the “renal factor” in cardiorenal syndrome that has become more relevant to both nephrologists and cardiologists. In addition, the prevention of renal replacement therapies via the optimization of medical therapy is the focus. Since the conception of this Special Issue, sodium-glucose-cotransporter-2 inhibitors have demonstrated a huge potential as cardiorenal medication in order to delay the onset of renal replacement therapies. Other upcoming medications, including finerenone, may add value as cardiorenal medications as well. Last, the pathogenesis of uremic cardiomyopathy, a new disease entity for heart failure during acute or chronic kidney failure is being reviewed in the upcoming Special Issue.

We are glad to have you here to follow up on these and other upcoming publications. Authors should feel free to submit their work. The diagnostics of and therapies for cardiorenal syndrome are topics of interest. We believe that this second edition will be an essential addition to the collective knowledge in the field.

Dr. Rainer Ullrich Pliquett
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • cardiorenal syndrome
  • outcome
  • hyperkalemia
  • acute kidney injury
  • chronic kidney disease
  • chronic heart failure

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Published Papers (1 paper)

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Research

13 pages, 1431 KiB  
Article
Venous Excess Ultrasound Score Is Associated with Worsening Renal Function and Reduced Natriuretic Response in Patients with Acute Heart Failure
by Sofya Sovetova, Kristina Charaya, Tamerlan Erdniev, Dmitry Shchekochikhin, Alexandra Bogdanova, Sergey Panov, Natalya Plaksina, Elmira Mutalieva, Natalia Ananicheva, Viktor Fomin and Denis Andreev
J. Clin. Med. 2024, 13(20), 6272; https://doi.org/10.3390/jcm13206272 - 21 Oct 2024
Viewed by 1116
Abstract
Background: The venous excess ultrasound score (VExUS) is used to objectify systemic venous congestion. The aim of the paper was to determine the association between VExUS grades and worsening renal function (WRF), reduced natriuretic response, diuretics resistance, and mortality in patients with acute [...] Read more.
Background: The venous excess ultrasound score (VExUS) is used to objectify systemic venous congestion. The aim of the paper was to determine the association between VExUS grades and worsening renal function (WRF), reduced natriuretic response, diuretics resistance, and mortality in patients with acute heart failure (AHF). Methods: One hundred patients were included, and Doppler ultrasound of hepatic, portal, and renal veins was performed. Severity of congestion was graded using the VExUS score (grade 0, 1, 2, or 3). Sodium concentration in a spot urine sample was assessed in 2 h after the first loop diuretic administration and was adjusted for the prescribed dose of furosemide (31 mmol/40 mg). Diuretics resistance was defined as the need to double the starting dose of intravenous furosemide in 6 h. Results: Patients with VExUS grade 3 showed a higher incidence of WRF (OR: 11.17; 95% CI: 3.86–32.29; p < 0.001) and a decreased natriuretic response: a spot urine sodium content of <50 mmol/L (OR: 21.53; 95% CI: 5.32–87.06; p < 0.001) and an adjusted spot urine sodium content of <31 mmol/40 mg (OR: 9.05; 95% CI: 3.15–25.96; p < 0.001). The risk of diuretic resistance (OR: 15.31; 95% CI: 5.05–46.43; p < 0.001), as well as the need for inotropic and/or vasopressor support (OR: 11.82; 95% CI: 3.59–38.92; p < 0.001), was higher in patients with severe congestion. The hospital mortality rate increased in patients with VExUS grade 3 compared to in patients with other grades (OR: 26.4; 95% CI: 5.29–131.55; p < 0.001). Conclusions: Patients with AHF and VExUS grade 3 showed a higher risk of developing WRF, a decreased diuretic and natriuretic response, a need for inotropic and/or vasopressor support, and a poor prognosis during their hospital stay. Full article
(This article belongs to the Special Issue New Advances in Cardiorenal Syndrome: 2nd Edition)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Sodium-glucose-cotransporter -2 inhibitor therapy in cardiorenal medicine - role of glucose-mediated oxidative stress
Authors: K. Schröder
Affiliation: Institut für Kardiovaskuläre Physiologie, Goethe-Universität, Frankfurt, Germany

Title: Uremic Cardiomyopathy presenting as acute heart failure with pericardial effusion: a case-series report and review of the literature.
Authors: A. Janikowsia
Affiliation: Germany

Title: Potassium-induced aldosterone activation as a therapeutic goal in cardiorenal syndrome
Authors: A. Adeagbo
Affiliation: Germany

Title: Acute kidney injury during sepsis: prognostic role of comorbidity heart failure
Authors: Jens Soukup
Affiliation: Germany

Title: Review of Bradycardia-associated Renal failure, Atrioventricular block, Shock, Hyperkalemia (BRASH) syndrome - a common cause of cardiorenal syndrome
Authors: R. Pliquett
Affiliation: Germany

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