Neuroimaging in 2024 and Beyond

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 10 March 2025 | Viewed by 343

Special Issue Editors


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Guest Editor
Neuroradiology Unit, Ospedale del Mare ASL NA1 Centro, Via Enrico Russo, 80147 Naples, Italy
Interests: interventional neuroradiology; MRI; neuroimaging

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Guest Editor
Department of Advanced Biomedical Sciences, University of Naples "Federico II", 80131 Naples, Italy
Interests: neuroradiology; neurological sciences; neurosurgery; brain tumor; head and neck pathology; radiomics
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Special Issue Information

Dear Colleagues,

In recent decades, neuroradiology has made indescribable progress. Technological advances have allowed for the development of diagnostic methods capable of providing images characterized by their high resolution of spatial anatomy (computerized tomography and magnetic resonance imaging), but also by informative content on tissue cellular characteristics, thanks to the development of sophisticated imaging techniques such as DWI MRI, spectroscopy MRI, and perfusion MRI. New trends in and future directions of research are developing and progressively modifying the traditional working methods of neuroradiologists around the world, increasingly implementing precision diagnostics, thanks to which imaging biomarkers of disease and responses to treatments can be identified.

Alongside precision diagnostics, interventional neuroradiology methods have also been developed in the endovascular and spinal fields that have radically changed the healthcare management of many neurological and neurosurgical pathologies.

Furthermore, there is growing momentum behind leveraging artificial intelligence techniques to improve workflows, diagnosis, and treatment, and to enhance the value of quantitative imaging techniques. We welcome the submission of articles that address technological advances and innovations in diagnostic, interventional, and experimental neuroradiology capable of changing daily clinical practice (as well as preclinical activity with translational perspectives) in various fields of medicine, such as neurology, neurosurgery, oncology, or radiotherapy.

We invite authors to submit articles on technological advances and innovations in diagnostic and interventional neuroradiology for this Special Issue, in order to better understand what can be identified as neuroimaging biomarkers capable of developing a precision diagnostic and therapeutic approach.

Dr. Alberto Negro
Dr. Lorenzo Ugga
Guest Editors

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Keywords

  • neuroimaging
  • neuroradiology
  • neuro-oncology
  • brain degenerative disease
  • magnetic resonance imaging
  • neurosurgery
  • neurology

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Published Papers (1 paper)

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Research

21 pages, 3538 KiB  
Article
Global and Regional Sex-Related Differences, Asymmetry, and Peak Age of Brain Myelination in Healthy Adults
by Marina Y. Khodanovich, Mikhail V. Svetlik, Anna V. Naumova, Anna V. Usova, Valentina Y. Pashkevich, Marina V. Moshkina, Maria M. Shadrina, Daria A. Kamaeva, Victoria B. Obukhovskaya, Nadezhda G. Kataeva, Anastasia Y. Levina, Yana A. Tumentceva and Vasily L. Yarnykh
J. Clin. Med. 2024, 13(23), 7065; https://doi.org/10.3390/jcm13237065 - 22 Nov 2024
Abstract
Background: The fundamental question of normal brain myelination in human is still poorly understood. Methods: Age-dependent global, regional, and interhemispheric sex-related differences in brain myelination of 42 (19 men, 23 women) healthy adults (19–67 years) were explored using the MRI method of [...] Read more.
Background: The fundamental question of normal brain myelination in human is still poorly understood. Methods: Age-dependent global, regional, and interhemispheric sex-related differences in brain myelination of 42 (19 men, 23 women) healthy adults (19–67 years) were explored using the MRI method of fast macromolecular fraction (MPF) mapping. Results: Higher brain myelination in males compared to females was found in global white matter (WM), most WM tracts, juxtacortical WM regions, and putamen. The largest differences between men and women, exceeding 4%, were observed bilaterally in the frontal juxtacortical WM; angular, inferior occipital, and cuneus WM; external capsule; and inferior and superior fronto-orbital fasciculi. The majority of hemispheric differences in MPF were common to men and women. Sex-specific interhemispheric differences were found in juxtacortical WM; men more often had left-sided asymmetry, while women had right-sided asymmetry. Most regions of deep gray matter (GM), juxtacortical WM, and WM tracts (except for projection pathways) showed a later peak age of myelination in women compared to men, with a difference of 3.5 years on average. Body mass index (BMI) was associated with higher MPF and later peak age of myelination independent of age and sex. Conclusions: MPF mapping showed high sensitivity to assess sex-related differences in normal brain myelination, providing the basis for using this method in clinics. Full article
(This article belongs to the Special Issue Neuroimaging in 2024 and Beyond)
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