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Corneal Surgery: Latest Advances and Prospects
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Corneal Surgery: Latest Advances and Prospects

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 1732

Special Issue Editors

Dr. Augusto Pocobelli

E-Mail Website
Guest Editor
San Giovanni Addolorata Hospital, UOC Oftalmologia, Banca degli Occhi, Rome, Italy
Interests: corneal surgery; keratoconus; cataract surgery; refractive surgery
Dr. Fabio Scarinci

E-Mail Website
Guest Editor
San Giovanni Addolorata Hospital, UOC Oftalmologia, Banca degli Occhi, Rome, Italy
Interests: corneal surgery; cataract surgery; refractive surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Corneal surgery and treatments have become an important addition to the ophthalmic procedure armamentarium in clinical practice, with corneal transplantation being the most performed transplant worldwide. Also, the latest advances in corneal surgery, including the use of new biomaterials and novel techniques such as laser platforms, have provided ophthalmologists with well-established and safer treatments to restore ocular integrity and the patient’s vision.

The availability of donated corneas, thanks to the activities of Eye Banks, is a prerequisite for successful transplantation and the accessibility of corneal tissue. The preservation methods encompass the responsibilities of procuring, preserving, ensuring quality control, and preparing tissues for the operation theater. Furthermore, in recent years, imaging analysis of the cornea has improved allowing for quantitative as well as qualitative evaluation of several corneal parameters that represent biomarkers of disease progression. While some novelties will not find an application in the clinical practice, others will be successful and will become fundamental for patient management.

This Special Issue seeks to outline studies targeting the latest developments in surgery for various corneal diseases.

Dr. Augusto Pocobelli
Dr. Fabio Scarinci
Guest Editors

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Keywords

  • corneal surgery
  • corneal diseases
  • deep anterior lamellar keratoplasty
  • descemet stripping automated endothelial keratoplasty
  • descemet membrane endothelial keratoplasty
  • keratoconus
  • eye bank

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Published Papers (2 papers)

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Research

11 pages, 831 KiB  
Article
Endothelial Keratoplasty Following Glaucoma Filtration Surgery: A UK Tertiary Eye Care Referral Centre Experience
by Francesco Aiello, Francesco Matarazzo, Maria Phylactou, Kirithika Muthusamy and Vincenzo Maurino
J. Clin. Med. 2024, 13(20), 6097; https://doi.org/10.3390/jcm13206097 - 13 Oct 2024
Viewed by 668
Abstract
Purpose: To compare the postoperative complications and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK) in eyes with previous glaucoma filtering surgery. Methods: In this retrospective comparative case series, we analysed postoperative visual acuity and intraocular [...] Read more.
Purpose: To compare the postoperative complications and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK) in eyes with previous glaucoma filtering surgery. Methods: In this retrospective comparative case series, we analysed postoperative visual acuity and intraocular pressure, graft survival, rate of graft detachment and/or dislocation, number of rebubbling and/or graft repositioning procedures, and graft rejection or failure (primary and secondary). Results: Sixteen eyes with DMEK and 80 eyes with DSAEK with previous glaucoma surgery were studied. The results were recorded at 3 and 12 months postoperatively. No statistically significant differences in postoperative visual acuity were found between the two groups at any stage of the follow-up. Intraocular pressure was lower in the DMEK group at the follow-up stage of 3 (p = 0.0022) and 12 months (p = 0.0480). Visually significant graft detachment was recorded in 31.3% and 22.5% of DMEK and DSAEK cases, respectively (p = 0.4541). All DMEK detachments (n = 5) were managed with slit-lamp rebubbling. Out of 18 graft detachments in the DSAEK group, 2 grafts were observed due to small graft detachment, 6 large graft detachments underwent rebubbling performed in the operating theatre, and 10 eyes needed primary graft repositioning for graft dislocation. Conclusions: DMEK is a feasible option to treat endothelial failure in complex eyes with previous glaucoma surgery. In the DMEK group, visual acuity outcomes and possibly postoperative intraocular pressure control were better compared with the DSAEK group. Full article
(This article belongs to the Special Issue Corneal Surgery: Latest Advances and Prospects)
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9 pages, 5590 KiB  
Article
Clinical Outcomes of Modified Manual Deep Anterior Lamellar Keratoplasty for Eyes with Previous Radial Keratotomy
by Francesco Aiello, Giulio Pocobelli, Alfonso Iovieno, Chiara Komaiha, Carlo Nucci and Augusto Pocobelli
J. Clin. Med. 2024, 13(17), 5250; https://doi.org/10.3390/jcm13175250 - 5 Sep 2024
Viewed by 632
Abstract
Background: The aim of this study was to evaluate the intraoperative complications and visual outcomes of manual deep anterior lamellar keratoplasty (mDALK) in patients who underwent previous radial keratotomy (RK) for myopia. Methods: The notes of patients who underwent mDALK after [...] Read more.
Background: The aim of this study was to evaluate the intraoperative complications and visual outcomes of manual deep anterior lamellar keratoplasty (mDALK) in patients who underwent previous radial keratotomy (RK) for myopia. Methods: The notes of patients who underwent mDALK after RK at three different hospitals—San Giovanni Addolorata Hospital (Rome, Italy), Mount Saint Joseph Hospital (Vancouver, Canada), and Tor Vergata University Hospital (Rome, Italy)—were retrospectively reviewed. We analyzed the manual dissection success rate and conversion to penetrating keratoplasty (PK), the residual recipient stromal thickness, the postoperative corrected distance visual acuity (CDVA), postoperative refraction, and topographic astigmatism. Results: Thirteen eyes of eleven patients were included in the analysis (male 7/11, 63.6%). Preoperatively, mean topographic astigmatism was 5.4 ± 3.5 D (range 1.6–14.8 D), and mean CDVA was 0.47 ± 0.2 logMAR (range 0.3–1.0 logMAR) [Snellen equivalent 20/50]. Manual dissection was performed in all cases. None of the examined eyes were converted to PK. An improvement in both topographic astigmatism (2.8 ± 0.9 D, p = 0.0135) and CDVA (0.23 ± 0.2 LogMAR, p = 0.0122) was recorded at 12-month follow-up. Conclusions: mDALK is a safe and effective surgical technique when applied to eyes previously treated with RK, with an observed improvement in CDVA and topographic astigmatism. Full article
(This article belongs to the Special Issue Corneal Surgery: Latest Advances and Prospects)
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