Controlled Release Technologies for Localized Drug Delivery
A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials for Drug Delivery".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 289
Special Issue Editors
Interests: drug delivery; nanomedicine; nose-to-brain delivery; brain targeting; design of experiment; quality by design
Special Issues, Collections and Topics in MDPI journals
Interests: nanomedicine; lipid nanoparticles; RNA delivery; nanosuspensions; microfluidics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
During the past two decades, significant advances have been made in the area of controlled drug delivery systems (DDSs) for the release of a variety of bioactive agents.
This great interest is the result of the growing awareness that by achieving predictable and reproducible release rates of bioactive molecules to the target district for a desired duration, optimum biological responses, decreased toxicity, as well as a reduction in the required dose level can be effectively achieved.
A number of controlled-release DDSs have been developed ranging from the macro and nano scale to intelligent targeted delivery, and some are already on the market.
The choice of biomaterial (polymers, polysaccharides, proteins, lipids, peptides) plays an important role in designing a DDS with defined physicochemical properties and drug release profiles. Furthermore, directing the drug to the site where the intended pharmacological activity is needed is of utmost importance to prevent the unwanted drug effects on other organs. To achieve localized delivery (i.e., specific or preferential distribution of drug molecules within a tissue/body organ), the design of a DDS must be guided by a deep knowledge of the anatomy, physiology, and biomolecular properties of the target site.
The present Special Issue aims to collect innovative ideas in the design of smart controlled release systems to specific districts of the body to achieve localized drug delivery.
Researchers are welcome to submit reviews and original research papers focusing on controlled DDSs (lipid-based drug carriers, polymeric particles, hydrogels, drug-eluting implants, etc.) designed to achieve localized drug delivery (brain targeting, ocular delivery, skin, colon delivery, etc.) exploiting different administration routes.
Dr. Angela Bonaccorso
Dr. Michele Schlich
Guest Editors
Manuscript Submission Information
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Keywords
- biopolymers
- immunoliposomes
- medical implants
- sustained release
- site-specific
- localized therapy
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