United Airway Disease: Current Perspectives

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Personalized Therapy and Drug Delivery".

Deadline for manuscript submissions: 25 December 2024 | Viewed by 1475

Special Issue Editors


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Guest Editor
1. Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20090 Milan, Italy
2. Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy
3. Otorhinolaryngology Head and Neck Surgery Unit, Casa di Cura Humanitas San Pio X, Via Francesco Nava 31, 20159 Milan, Italy
Interests: rhinology; otorhinolaryngology; biologics; immunology; allergology; pneumology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Campus Bio-Medico University of Rome, School of Medicine, Via A. del Portillo 200, 00128 Rome, Italy
Interests: rehabilitation medicine; speech and language pathology; otolaryngology; respiratory tract infection; upper airways inflammation; nasal septal deformities

Special Issue Information

Dear Colleagues,

We are pleased to announce this Special Issue, which is aimed at enhancing the central role of the respiratory system in regulating homeostasis of the whole body. Also, when dysregulated, it is responsible for a significant socioeconomic burden and several clinical conditions with possible multi-organ failure may occur.

Searching for possible associations between different respiratory disorders, such as nasal congestion, allergy and asthma, entails personalizing medical treatment. Identifying the inflammatory profile of diseased patients contributes to predicting the effectiveness of medical and surgical therapeutic strategies. Also, studying the interaction between respiratory symptoms and poor sleep quality, asthenia, restlessness, or drowsiness may help intercept undiagnosed sleep disorders, thus preventing the serious cardiovascular consequences of sleep apnoea.

Nowadays, interest in the respiratory systems is increasing, as specialists are facing ever more clinical challenges. Recent advances in clinical immunology, which resulted in the approval of monoclonal antibodies for the treatment of chronic severe type-2 inflammation, have boosted this process further. These challenges entail the creation of multidisciplinary approaches aimed at keeping the patient at the centre of the treatment plan, from diagnostics to treatment proposals and follow-up (i.e., participation).

From this standpoint, this Special Issue is focused on exploring current perspectives, as well as on shining a spotlight on the most recent advances in both the diagnostic and therapeutic aspects of united airway diseases. As such, we invite the submission of contributions by different specialists whose professional experience encompasses a multidisciplinary approach to such conditions (e.g., allergologists, pneumologists, rhinologists, etc.), bearing in mind a personalized medicine approach. 

Prof. Dr. Luca Malvezzi
Prof. Dr. Manuele Casale
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chronic rhinosinusitis
  • asthma
  • personalized medicine
  • type-2 inflammation
  • united airway
  • obstructive sleep apnoea
  • monoclonal antibodies
  • endotype
  • rhinology

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Published Papers (1 paper)

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14 pages, 541 KiB  
Systematic Review
The Potential Effect of Changing Patient Position on Snoring: A Systematic Review
by Antonio Moffa, Lucrezia Giorgi, Domiziana Nardelli, Francesco Iafrati, Giannicola Iannella, Giuseppe Magliulo, Peter Baptista, Claudio Vicini and Manuele Casale
J. Pers. Med. 2024, 14(7), 715; https://doi.org/10.3390/jpm14070715 - 2 Jul 2024
Viewed by 1162
Abstract
Approximately 45% of adults snore occasionally, and 25% snore regularly, with a higher prevalence in men and an increase among postmenopausal women due to hormonal changes. Snoring is a health concern linked to vascular disease and decreased quality of life for both snorers [...] Read more.
Approximately 45% of adults snore occasionally, and 25% snore regularly, with a higher prevalence in men and an increase among postmenopausal women due to hormonal changes. Snoring is a health concern linked to vascular disease and decreased quality of life for both snorers and their bed partners. Effective snoring treatment, which aims to reduce or eliminate the sound, is challenging and depends on factors like age, comorbidities, disease severity, and anatomical features. This review aims to provide a systematic overview of the current literature on the effects of positional therapy (PT) on snoring. Various devices facilitate PT, including anti-snoring pillows and vibration alarms. PT devices maintain head and neck alignment to keep airways open, while head of bed elevation (HOBE) solutions reduce upper airway collapses by elevating the head and trunk. Studies show that PT and HOBE reduce snoring by increasing airway cross-sectional area and decreasing closing pressure. Despite their benefits, these non-surgical treatments have limitations, such as discomfort in certain sleeping positions and intolerance to prolonged head elevation. While reducing snoring intensity is critical for health reasons, further comparative studies between the different devices are needed to enhance snoring management. Full article
(This article belongs to the Special Issue United Airway Disease: Current Perspectives)
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