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Otorhinolaryngology (Head and Neck Surgery): Personalized Diagnostics and Therapy
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Otorhinolaryngology (Head and Neck Surgery): Personalized Diagnostics and Therapy

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Personalized Therapy and Drug Delivery".

Deadline for manuscript submissions: 25 February 2025 | Viewed by 674

Special Issue Editor

Dr. Jee Hye Wee

E-Mail Website
Guest Editor
Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang 14068, Republic of Korea
Interests: rhinology; allergic rhinitis; sleep apnea; chronic rhinosinusitis

Special Issue Information

Dear Colleagues,

Otorhinolaryngology (head and neck surgery), focusing on ear, nose, and throat (ENT) disorders, is a field that has significantly benefited from advances in personalized medicine. Traditionally, treatments in otorhinolaryngology were generalized, with a one-size-fits-all approach applied to the management of conditions such as hearing loss, sinusitis, allergies, sleep apnea, voice disorders, and multiple types of cancer, etc. However, recent developments in diagnostics and therapy have shifted towards a more personalized approach, driven by the unique genetic, environmental, and lifestyle factors of each patient. The concept of personalized medicine in otolaryngology has evolved over the past few decades. Initially, the management of ENT disorders relied heavily on broad-spectrum medications and invasive surgical procedures with variable outcomes. The introduction of genomic medicine, improved imaging techniques, and advanced surgical technologies have transformed the landscape.

The Special Issue aims to explore and disseminate cutting-edge research that highlights the shift towards personalized care in the field of otorhinolaryngology.  This Special Issue seeks to foster a deeper understanding of how personalized approaches can be effectively implemented in otorhinolaryngology, aiming to enhance patient outcomes through more tailored and precise medical care. By featuring a mix of research articles, reviews, and case studies, this issue aims to be a valuable resource for clinicians, researchers, and healthcare professionals committed to advancing the field of personalized medicine in otorhinolaryngology. Original research, review articles, and communications are welcomed.

Dr. Jee Hye Wee
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • allergic rhinitis
  • chronic rhinosinusitis
  • hearing loss
  • dizziness
  • sleep apnea
  • voice disorder
  • head and neck cancer
  • thyroid cancer

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Published Papers (1 paper)

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Research

13 pages, 2686 KiB  
Article
Influence of Pre-Operative Estimation of Draf III Expected Diameter on Surgical Outcome
by Matteo Alicandri-Ciufelli, Carla Cantaffa, Margherita Basso, Vito Colacurcio, Daniele Marchioni and Daniela Lucidi
J. Pers. Med. 2024, 14(9), 951; https://doi.org/10.3390/jpm14090951 - 9 Sep 2024
Viewed by 474
Abstract
Introduction: The DRAF III procedure is indicated for the treatment of benign and selected malignant frontal sinus pathology. Several attempts have been made to find an intra or pre-operative measurement that was predictive of the feasibility of this operation and its success. [...] Read more.
Introduction: The DRAF III procedure is indicated for the treatment of benign and selected malignant frontal sinus pathology. Several attempts have been made to find an intra or pre-operative measurement that was predictive of the feasibility of this operation and its success. Among those, the frontal sinus outflow tract anteroposterior diameter (FOAP) appears to be the one with the highest applicability in clinical practice, since it is easy to measure on pre-operative CT scan. The objective of the study is to evaluate whether the minimum and maximum frontal sinus outflow anteroposterior diameters (FOAP min and FOAP max) are associated with the risk of failure and consequently with the need for surgical revision. Secondly, we ought to evaluate whether the angle between the glabella and the nasion on the sagittal plane could influence surgical outcome. Material and Methods: This is a retrospective study on patients who underwent DRAF III for benign pathologies at a tertiary Italian referral center from January 2000 to July 2022. FOAP min and FOAP max were measured on the mid-sagittal sections of a pre-operative CT scan. The glabella–nasion angle (G-N angle) was calculated on the same sagittal section. These measurements were compared between patients who experienced a recurrence and those who did not. If a post-operative CT scan was available, the obtained anteroposterior diameter (OD) of the frontal sinus neo-ostium was also measured on the same section. A correlation analysis was performed between the three pre-operative radiologic parameters and OD. Results: Twenty-nine patients were included in the study. Six patients experienced restenosis requiring surgical revision. The median FOAP max resulted significantly higher in patients who did not experience recurrence (median: 14.8 mm, IQR: 3.84) than in patients who experienced a recurrence (median: 11.9 mm, IQR: 1.14) (p = 0.04). The FOAP max also showed a good positive correlation with OD (p = 0.0001; r = 0.7). The correlation between FOAP min and OD was not statistically significant, nor was a correlation found between FOAP min and recurrence risk. The G-N angle was not significantly different in patients who experienced recurrence and those who did not, nor did it show a correlation with OD. Discussion: The FOAP max might be a valid pre-operative radiologic parameter to guide a surgeon’s approach to a DRAF III procedure, as it is easy to measure, shows a good correlation with OD, and seems to influence the risk of recurrence. Full article
(This article belongs to the Special Issue Otorhinolaryngology (Head and Neck Surgery): Personalized Diagnostics and Therapy)
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