Skin Cancers: Update on Personalized Treatment and Management

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Personalized Therapy and Drug Delivery".

Deadline for manuscript submissions: 20 February 2025 | Viewed by 805

Special Issue Editor


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Guest Editor
1. Department of Physiopathology and Transplantation, University of Milan, 20122 Milan, Italy
2. Dermatology Unit, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy
Interests: dermoscopy; dermatopathology; tropical dermatology; ultrasonography; history of medicine

Special Issue Information

Dear Colleagues,

Skin cancers, including basal cell carcinoma, squamous cell carcinoma, and melanoma, have continued to rise globally over the past few decades, and statistics have shown that skin cancer is one of the three most common forms of cancer. Fortunately, novel, more effective treatments for various types of skin cancer are in development, and early diagnosis and the exploration of innovative treatments are particularly important.

This Special Issue will focus on recent advances in skin cancer prevention, diagnosis, and treatment and the latest insights gained by clinical researchers, with a focus on how to personalize these new advances in clinical practice.

Dr. Nazzaro Gianluca
Guest Editor

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Keywords

  • basal cell carcinoma
  • squamous cell carcinoma
  • melanoma
  • skin cancers
  • dermoscopy
  • ultrasonography
  • immunotherapy
  • biomarker
  • prevention
  • diagnosis
  • treatment
  • innovative treatments
  • prognosis
  • personalized

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Published Papers (1 paper)

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8 pages, 1608 KiB  
Case Report
Electrochemotherapy Treatment in a Patient with an Extended Basal Cell Carcinoma of the Face: A Case Report
by Francesco Russano, Davide Brugnolo, Giovanni Bisetto, Paolo Del Fiore, Marco Rastrelli, Simone Mocellin and Luigi Dall’Olmo
J. Pers. Med. 2024, 14(9), 984; https://doi.org/10.3390/jpm14090984 - 16 Sep 2024
Viewed by 568
Abstract
Background. Basal cell carcinomas (BCCs) are common human malignancies with a rising incidence in recent years. While BCCs have a low mortality rate, they are often associated with significant local skin damage characterized by erythema, skin ulceration, and persistent pigmentation. Surgery, radiotherapy, and [...] Read more.
Background. Basal cell carcinomas (BCCs) are common human malignancies with a rising incidence in recent years. While BCCs have a low mortality rate, they are often associated with significant local skin damage characterized by erythema, skin ulceration, and persistent pigmentation. Surgery, radiotherapy, and systemic chemotherapy have traditionally been the principal treatments for these skin injuries. However, electrochemotherapy has recently been proposed as a novel local treatment with promising results for various skin cancers, including BCC, while avoiding the side effects of conventional therapies. ECT involves a local electrical stimulus that enhances cell membrane permeability, thereby enabling the targeted intracellular accumulation of the chemotherapeutic agent. Case Report: We report a case of a 68-year-old man with an ulcerated BCC, following his progress up to 14 months post-ECT treatment, with positive outcomes. Discussion and Conclusions: We achieved a complete clinical response and noted an improvement in the patient’s quality of life. This technique is fast, repeatable, requires minimal hospitalization, and reduces healthcare costs and adverse effects compared to major surgery. Therefore, it can be considered an alternative or complementary approach to traditional surgery for treating BCC of the head and neck. Full article
(This article belongs to the Special Issue Skin Cancers: Update on Personalized Treatment and Management)
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