Marine Microalgal Biorefinery for Bioactive Compound Production 2024

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Biotechnology Related to Drug Discovery or Production".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1314

Special Issue Editor


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Guest Editor
Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China
Interests: microalgae; lipids; polyunsaturated fatty acids; metabolic engineering; fermentation engineering

Special Issue Information

Dear Colleagues,

Given the sustainable status of marine microalgae as raw materials, their conversion into bioproducts is currently celebrated as a green solution with the potential to alleviate various challenges. In recent years, extensive research has been conducted on biotechnology and bioprocessing, aiming to enhance the technical and economic feasibility of producing bioproducts from various sources. Specifically, the development of synthetic biology and artificial intelligence has opened up opportunities for maximizing the potential productivity of marine microalgae. This special issue invites original research papers and reviews that focus on the latest innovative developments in marine microalgal bioprocess engineering, including upstream biotechnological advancements, downstream separation and purification processes, as well as discussions on the efficiency of the entire product and process lifecycle.

Dr. Xiaojin Song
Guest Editor

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Keywords

  • bioengineering technologies
  • bioproducts
  • cultivation
  • fermentation
  • high throughput screening
  • marine microalgae
  • metabolic engineering
  • separation and purification processes
  • synthetic biology

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Published Papers (1 paper)

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Research

18 pages, 8210 KiB  
Article
Comprehensive Assessment of Herbicide Toxicity on Navicula sp. Algae: Effects on Growth, Chlorophyll Content, Antioxidant System, and Lipid Metabolism
by Chunyan Zheng, Jie Yang, Yunting Wang, Waqas Ahmed, Amir Khan, Jiannan Li, Jiechang Weng, Sajid Mehmood and Weidong Li
Mar. Drugs 2024, 22(9), 387; https://doi.org/10.3390/md22090387 - 28 Aug 2024
Viewed by 1027
Abstract
This study investigated the effects of herbicide exposure on Navicula sp. (MASCC-0035) algae, focusing on growth density, chlorophyll content, antioxidant system, and lipid metabolism. Navicula cultures were exposed to different concentrations of atrazine (ATZ), glyphosate (Gly), and acetochlor (ACT) for 96 h. Results [...] Read more.
This study investigated the effects of herbicide exposure on Navicula sp. (MASCC-0035) algae, focusing on growth density, chlorophyll content, antioxidant system, and lipid metabolism. Navicula cultures were exposed to different concentrations of atrazine (ATZ), glyphosate (Gly), and acetochlor (ACT) for 96 h. Results showed a significant decrease in cell numbers, with higher herbicide concentrations having the most noticeable impacts. For instance, Gly-G2 had reduced cell populations by 21.00% at 96 h. Chlorophyll content varied, with Gly having a greater impact on chlorophyll a compared to ATZ and ACT. Herbicide exposure also affected the antioxidant system, altering levels of soluble sugar, soluble protein, and reactive oxygen species (ROS). Higher herbicide rates increased soluble sugar content (e.g., ATZ, Gly, and ACT-G2 had increased by 14.03%, 19.88%, and 19.83%, respectively, at 72 h) but decreased soluble protein content, notably in Gly-G2 by 11.40%, indicating cellular stress. Lipid metabolism analysis revealed complex responses, with changes in free proline, fatty acids, and lipase content, each herbicide exerting distinct effects. These findings highlight the multifaceted impacts of herbicide exposure on Navicula algae, emphasizing the need for further research to understand ecological implications and develop mitigation strategies for aquatic ecosystems. Full article
(This article belongs to the Special Issue Marine Microalgal Biorefinery for Bioactive Compound Production 2024)
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