Synthetic Studies of Marine Bioactive Natural Products and Analogs to Develop Novel Drug Leads
A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Synthesis and Medicinal Chemistry of Marine Natural Products".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 907
Special Issue Editor
Special Issue Information
Dear Colleagues,
Marine natural products are considered promising sources of drug candidates, especially in the field of anticancer drugs or antibiotics. However, the scarce supply of compounds from natural sources often limits further drug development. On the other hand, efficient total synthesis of marine natural products and their derivatives can overcome this drawback. In addition, the synthesis of truncated analogs based on structure–activity relationship (SAR) studies would facilitate the discovery of more accessible drug lead compounds with improved bioactive specificity or ADMET profiles.
Therefore, the Special Issue will focus on the synthetic studies of bioactive marine natural products and their derivatives. Submissions on the development of truncated analogs leading to novel drug leads are also welcome.
Prof. Dr. Naoyuki Kotoku
Guest Editor
Manuscript Submission Information
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Keywords
- marine natural products
- total synthesis
- synthetic derivatives
- truncated analogs
- structure–activity relationship
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