Scaffold Diversity of Marine Natural Products

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Synthesis and Medicinal Chemistry of Marine Natural Products".

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 3944

Special Issue Editor


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Guest Editor
Department of Organic Chemistry, Faculty of Sciences, University of Malaga, 29071 Málaga, Spain
Interests: natural product; organic chemistry; new drug discovery; synthesis
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Special Issue Information

Dear Colleagues,             

Scaffold diversity is a crucial feature of compound collections that has a huge impact on their success in biological screenings. Marine natural products are characterized by high chemical diversity and may be an excellent platform to build compound libraries with an important degree of scaffold diversity. A promising method in the endless search for new drugs can rely on the exploration of the new chemical space. Therefore, marine natural products and their related molecules can inspire diverse synthetic strategies directed towards the study of that underexplored chemical space.

This Special Issue aims to collect original research articles regarding different synthetic plans where marine natural products can serve as a breakpoint to create scaffold diversity and enable further biological testing.

Prof. Dr. Miguel García-Castro
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • marine natural products
  • scaffold diversity
  • chemical space

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Published Papers (1 paper)

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Review

47 pages, 12167 KiB  
Review
Transition-Metal-Catalyzed Transformations for the Synthesis of Marine Drugs
by Lucía G. Parte, Sergio Fernández, Eva Sandonís, Javier Guerra and Enol López
Mar. Drugs 2024, 22(6), 253; https://doi.org/10.3390/md22060253 - 29 May 2024
Viewed by 3530
Abstract
Transition metal catalysis has contributed to the discovery of novel methodologies and the preparation of natural products, as well as new chances to increase the chemical space in drug discovery programs. In the case of marine drugs, this strategy has been used to [...] Read more.
Transition metal catalysis has contributed to the discovery of novel methodologies and the preparation of natural products, as well as new chances to increase the chemical space in drug discovery programs. In the case of marine drugs, this strategy has been used to achieve selective, sustainable and efficient transformations, which cannot be obtained otherwise. In this perspective, we aim to showcase how a variety of transition metals have provided fruitful couplings in a wide variety of marine drug-like scaffolds over the past few years, by accelerating the production of these valuable molecules. Full article
(This article belongs to the Special Issue Scaffold Diversity of Marine Natural Products)
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