Marine-Derived Polyketides with Antibiotic Activity
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (15 May 2019) | Viewed by 12420
Special Issue Editor
Interests: specialized metabolites; biosynthesis; drug discovery; anti-infectives Interests: antibiotics; heterologous expression; metabolomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Polyketides are a class of specialized metabolites produced by a wide variety of organisms. Most intriguing is the fact that these compounds show a multitude of biological activities, e.g., antibacterial activities. They are in the focus of research from an ecological, as well as pharmaceutical point of view, since many medicinal drugs are natural polyketides per se, or are based on them. Hence, polyketides possess the potential to become leads for novel medicinal drugs. Especially in the antibiotics field exists a pressing need to identify and evaluate novel structures. The current drugs, contributing to the increased life expectancy of humans, are losing their power due to antimicrobial resistance development and dispersion.
The goal of this Marine Drugs Special Issue is to assemble a collection of scientific articles outlining the diversity, the biosynthesis and the antibiotic potential of marine-derived polyketides.
Scientists from various fields are invited to contribute, to combine interdisciplinary expertise in marine-derived polyketides research, e.g., (micro)biology, analytical chemistry, bioinformatics, pharmacy, and biotechnology.
Prof. Dr. Till F. Schäberle
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- Polyketide
- PKS
- Mixed PKS/NRPS
- natural product
- secondary metabolite
- specialized metabolite
- biosynthesis
- antibiotic
- antibacterial
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