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Membranes
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Development and Applications of Electrospun Nanofiber Membrane
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Development and Applications of Electrospun Nanofiber Membrane

A special issue of Membranes (ISSN 2077-0375). This special issue belongs to the section "Membrane Applications".

Deadline for manuscript submissions: closed (20 June 2022) | Viewed by 17504

Special Issue Editors

Dr. Yen Truong

E-Mail Website
Guest Editor
CSIRO Manufacturing, Private Bag 10, Clayton, 3168 Victoria, Australia
Interests: materials science; membranes; polymers; electrospinning; nanofiber; composite nanofiber; biomaterial; tissue engineering; antimicrobial; controlled release; filtration; air filtration; water purification and gas adsorption
Dr. Nesrin Horzum

E-Mail Website
Guest Editor
Department of Engineering Sciences, İzmir Katip Celebi University, 35620, Çiğli, İzmir, Turkey
Interests: electrospinning; nanofiber; composite nanofiber; filtration; colorimetric detection; biomaterial; biosensors; materials science; membranes; polymers; antimicrobial; controlled release

Special Issue Information

Dear Colleagues,

Electrospinning, a variant of electro-spraying is a technique to produce nanofiber. The collection of these nanofibers results in an electrospun nanofiber membrane.  Due to being lightweight, having high surface area and interconnected pore structure, electrospun nanofiber membranes are useful for many health, energy and environment applications.  Electrospun nanofiber membranes are either organic or inorganic. They can be developed from both natural and synthetic polymers.

The COVID-19 pandemic caused concerns about the potential shortage of personal protective equipment. Adequate supply of medical face masks that met standard requirements for the protection for healthcare workers was one of those concerns. In Melbourne, Australia, between 19 July 2020 and 10 October 2020 any face covering including face shields, bandanas, or scarves were acceptable when you are a public area. However, since 11 October 2020, it has been compulsory for people in Melbourne (Victoria, Australia) to wear a proper facemask when they are outside of their homes.  Currently on the spot fines of $200 can be issued to people in Melbourne not wearing a mask without a valid excuse. Since February 2020, a worldwide shortage of supplies of medical face masks has prompted researchers in nanofiber membranes to apply their skills to manufacture a component for use in a multilayer composite face mask material. The production of medical face masks is an example of the application of electrospun nanofiber membranes in the health area. Additionally, electrospun membranes have been applied in many other health applications such tissue engineering, drug delivery, wound dressing, biosensors, antimicrobial filter, haemostatic devices and protective clothing.

Electrospun nanofiber membranes have also been extensively applied in the energy and environmental areas. They have been successfully demonstrated for use as battery separators, battery electrodes, solar cells, fuel cells, hydrogen storage and printable electronics and are useful in environmental areas such as separation membranes, affinity membranes and as filter media.

Electrospun nanofiber membranes have also been employed in the food area as on farm crop protection in the field and as packaging materials for prolonging shelf life of fruit.

This Special Issue aims to focus on recent research efforts and advances in the development and applications of electrospun nanofiber membranes for different research areas benefiting humankind.

Dr. Yen Truong
Dr. Nesrin Horzum
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Membranes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Electrospin/electrospun
  • Nanofiber
  • Membranes
  • Water treatment
  • Protective clothing
  • Tissue engineering/medical applications
  • Energy applications
  • Packaging materials

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Published Papers (4 papers)

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Research

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16 pages, 1555 KiB  
Article
Development and Characterizations of Engineered Electrospun Bio-Based Polyurethane Containing Essential Oils
by Nehir Arik, Nesrin Horzum and Yen Bach Truong
Membranes 2022, 12(2), 209; https://doi.org/10.3390/membranes12020209 - 10 Feb 2022
Cited by 14 | Viewed by 2636
Abstract
We report the fabrication of bio-based thermoplastic polyurethane (TPU) fibrous scaffolds containing essential oils (EO). The main goal of this study was to investigate the effects of essential oil type (St. John’s Wort oil (SJWO), lavender oil (LO), and virgin olive oil (OO))/concentration [...] Read more.
We report the fabrication of bio-based thermoplastic polyurethane (TPU) fibrous scaffolds containing essential oils (EO). The main goal of this study was to investigate the effects of essential oil type (St. John’s Wort oil (SJWO), lavender oil (LO), and virgin olive oil (OO))/concentration on the electrospinnability of TPU. The effects of applied voltage, flow rate, and end-tip distance on the diameter, morphology, and wettability of the TPU/EO electrospun fibers were investigated. The electrospun TPU/EO scaffolds were characterized by scanning electron microscopy (SEM), atomic force microscopy (AFM), contact angle (CA), and Fourier transform infrared spectroscopy (FTIR). The addition of oil resulted in an increase in the fiber diameter, reduction in the surface roughness, and, accordingly, a reduction in the contact angle of the composite fibers. TPU fibers containing SJWO and LO have a more flexible structure compared to the fibers containing OO. This comparative study fills the existing information gap and shows the benefits of the fabrication of essential-oil-incorporated electrospun fiber with morphology and size range with respect to the desired applications, which are mostly wound dressing and food packaging. Full article
(This article belongs to the Special Issue Development and Applications of Electrospun Nanofiber Membrane)
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13 pages, 4907 KiB  
Article
Argon and Argon–Oxygen Plasma Surface Modification of Gelatin Nanofibers for Tissue Engineering Applications
by Abolfazl Mozaffari, Mazeyar Parvinzadeh Gashti, Mohammad Mirjalili and Masoud Parsania
Membranes 2021, 11(1), 31; https://doi.org/10.3390/membranes11010031 - 2 Jan 2021
Cited by 41 | Viewed by 4385
Abstract
In the present study, we developed a novel approach for functionalization of gelatin nanofibers using the plasma method for tissue engineering applications. For this purpose, tannic acid-crosslinked gelatin nanofibers were fabricated with electrospinning, followed by treatment with argon and argon–oxygen plasmas in a [...] Read more.
In the present study, we developed a novel approach for functionalization of gelatin nanofibers using the plasma method for tissue engineering applications. For this purpose, tannic acid-crosslinked gelatin nanofibers were fabricated with electrospinning, followed by treatment with argon and argon–oxygen plasmas in a vacuum chamber. Samples were evaluated by using scanning electron microscopy (SEM), atomic force microscopy (AFM), attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy, contact angle (CA) and X-ray diffraction (XRD). The biological activity of plasma treated gelatin nanofibers were further investigated by using fibroblasts as cell models. SEM studies showed that the average diameter and the surface morphology of nanofibers did not change after plasma treatment. However, the mean surface roughness (RMS) of samples were increased due to plasma activation. ATR-FTIR spectroscopy demonstrated several new bands on plasma treated fibers related to the plasma ionization of nanofibers. The CA test results stated that the surface of nanofibers became completely hydrophilic after argon–oxygen plasma treatment. Finally, increasing the polarity of crosslinked gelatin after plasma treatment resulted in an increase of the number of fibroblast cells. Overall, results expressed that our developed method could open new insights into the application of the plasma process for functionalization of biomedical scaffolds. Moreover, the cooperative interplay between gelatin biomaterials and argon/argon–oxygen plasmas discovered a key composition showing promising biocompatibility towards biological cells. Therefore, we strongly recommend plasma surface modification of nanofiber scaffolds as a pretreatment process for tissue engineering applications. Full article
(This article belongs to the Special Issue Development and Applications of Electrospun Nanofiber Membrane)
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13 pages, 3781 KiB  
Article
Electrospun PCL Patches with Controlled Fiber Morphology and Mechanical Performance for Skin Moisturization via Long-Term Release of Hemp Oil for Atopic Dermatitis
by Sara Metwally, Daniel P. Ura, Zuzanna J. Krysiak, Łukasz Kaniuk, Piotr K. Szewczyk and Urszula Stachewicz
Membranes 2021, 11(1), 26; https://doi.org/10.3390/membranes11010026 - 31 Dec 2020
Cited by 24 | Viewed by 4460
Abstract
Atopic dermatitis (AD) is a chronic, inflammatory skin condition, caused by wide genetic, environmental, or immunologic factors. AD is very common in children but can occur at any age. The lack of long-term treatments forces the development of new strategies for skin regeneration. [...] Read more.
Atopic dermatitis (AD) is a chronic, inflammatory skin condition, caused by wide genetic, environmental, or immunologic factors. AD is very common in children but can occur at any age. The lack of long-term treatments forces the development of new strategies for skin regeneration. Polycaprolactone (PCL) is a well-developed, tissue-compatible biomaterial showing also good mechanical properties. In our study, we designed the electrospun PCL patches with controlled architecture and topography for long-term release in time. Hemp oil shows anti-inflammatory and antibacterial properties, increasing also the skin moisture without clogging the pores. It can be used as an alternative cure for patients that do not respond to traditional treatments. In the study, we tested the mechanical properties of PCL fibers, and the hemp oil spreading together with the release in time measured on skin model and human skin. The PCL membranes are suitable material as patches or bandages, characterized by good mechanical properties and high permeability. Importantly, PCL patches showed release of hemp oil up to 55% within 6 h, increasing also the skin moisture up to 25%. Our results confirmed that electrospun PCL patches are great material as oil carriers indicating a high potential to be used as skin patches for AD skin treatment. Full article
(This article belongs to the Special Issue Development and Applications of Electrospun Nanofiber Membrane)
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Review

Jump to: Research

13 pages, 1406 KiB  
Review
Bioactive Agent-Loaded Electrospun Nanofiber Membranes for Accelerating Healing Process: A Review
by Seyyed-Mojtaba Mousavi, Zohre Mousavi Nejad, Seyyed Alireza Hashemi, Marjan Salari, Ahmad Gholami, Seeram Ramakrishna, Wei-Hung Chiang and Chin Wei Lai
Membranes 2021, 11(9), 702; https://doi.org/10.3390/membranes11090702 - 13 Sep 2021
Cited by 50 | Viewed by 4666
Abstract
Despite the advances that have been achieved in developing wound dressings to date, wound healing still remains a challenge in the healthcare system. None of the wound dressings currently used clinically can mimic all the properties of normal and healthy skin. Electrospinning has [...] Read more.
Despite the advances that have been achieved in developing wound dressings to date, wound healing still remains a challenge in the healthcare system. None of the wound dressings currently used clinically can mimic all the properties of normal and healthy skin. Electrospinning has gained remarkable attention in wound healing applications because of its excellent ability to form nanostructures similar to natural extracellular matrix (ECM). Electrospun dressing accelerates the wound healing process by transferring drugs or active agents to the wound site sooner. This review provides a concise overview of the recent developments in bioactive electrospun dressings, which are effective in treating acute and chronic wounds and can successfully heal the wound. We also discuss bioactive agents used to incorporate electrospun wound dressings to improve their therapeutic potential in wound healing. In addition, here we present commercial dressings loaded with bioactive agents with a comparison between their features and capabilities. Furthermore, we discuss challenges and promises and offer suggestions for future research on bioactive agent-loaded nanofiber membranes to guide future researchers in designing more effective dressing for wound healing and skin regeneration. Full article
(This article belongs to the Special Issue Development and Applications of Electrospun Nanofiber Membrane)
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