Phytochemicals and Pharmacological Significance of Plant Secondary Metabolites in Medicine
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Plant Metabolism".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 82
Special Issue Editors
Interests: isolation and identification of natural compounds; metabolism of natural products by gut microbiota; inflammation diseases of the colon; compounds’ structure–activity relationship; green solvents
Interests: evaluation of mechanisms of disturbance of signaling pathways in experimental dysfunction of cellular metabolism; exploration and identification of molecular targets of experimental cancer pharmacotherapy and mechanisms of drug action
Special Issue Information
Dear Colleagues,
This Special Issue, titled “Phytochemicals and Pharmacological Significance of Plant Secondary Metabolites in Medicine”, will contain a selection of papers dealing with the phytochemical characterization of plant products and health-related natural-origin bioactive substances. Original research reports, review articles and commentaries are welcome. Natural plant products have been used for a long time as medicine to treat a variety of diseases. Most of the discovered drugs are either drugs of natural origin or synthetic derivatives of natural compounds. Plants produce a variety of secondary metabolites important in an ecological context; however, some of these metabolites also show health-promoting activities (such as flavonoids, phenolic acids, terpenoids or alkaloids). Thus, a multidisciplinary approach to drug discovery and molecular diversity from natural product sources needs to be combined to provide the best solution to the problems related to drug discovery and development. Moreover, the association between natural compounds with other drugs that are easily reachable on the pharmaceutical market may contribute an increase in their efficacy or in a reduction of their toxicity. This Special Issue aims to cover all aspects of natural bioactive plant products, including the isolation and chemical characterization of natural compounds; their in vitro, ex vivo and in vivo activities; mechanisms of action; structure–activity relationships; and pharmacokinetic and pharmacodynamic properties.
Dr. Katarzyna Jakimiuk
Dr. Arkadiusz Surażyński
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- natural plant products
- biological and pharmacological activity
- isolation
- disease prevention and treatment
- natural plant drug discovery
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