Clinical and Therapeutic Implications of Metabolomics in Cancer Immunology

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Cell Metabolism".

Deadline for manuscript submissions: closed (20 April 2024) | Viewed by 278

Special Issue Editor


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Guest Editor
Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA
Interests: cancer research; hormones; cell-death; molecular alterations; cell signaling; tumor microenvironment; cellular plasticity; metabolism and endocrinology
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Special Issue Information

Dear Colleagues,

Metabolomics, a relatively recent addition to the "omics" sciences, delves into the study of the metabolome, which comprises bioactive molecules present in biological samples. These molecules play a versatile role in regulating various biological and immunological functions. In biological studies, clinical metabolomics has emerged as a complementary discipline.

A particularly encouraging avenue in scientific inquiry, especially within biomedical and clinical cancer research, is immuno-metabolomics. This approach has yielded novel perspectives across various scientific disciplines/domains. Notably, it focuses on unraveling the metabolic signatures associated with the immune system, with a specific emphasis on understanding the factors influencing the physiological and pathological conditions. This line of investigation holds immense potential for preventing, diagnosing, and treating cancer patients, especially those who confront elevated levels of illness and mortality.

This Special Issue will feature reviews and original research articles on innovative methods for the metabolic profiling of immune response, with applications in immune-related pathological conditions. Of particular significance is a study on metabolomic profiles with implications for clinical oncology, employing diverse analysis platforms. Additionally, we will highlight how metabolic changes across cells within the tumor microenvironment can impact immune cell function, potentially influencing the outcomes of immune responses. Therapy resistance remains a critical concern in the field of cancer biology. Consequently, research that employs metabolomics to discover novel target molecules or potential drug targets will be given significant consideration.

Dr. Jyoti Kaushal
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metabolites
  • immune cells
  • clinical oncology
  • tumor microenvironment
  • immunometabolism

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Published Papers

There is no accepted submissions to this special issue at this moment.
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