Obesity and Metabolic Health
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".
Deadline for manuscript submissions: 5 January 2025 | Viewed by 403
Special Issue Editors
Interests: neuroinflammation; neuroimmunology, glial cells, obesity, metabolism, fetal metabolic programming; gut microbiota; liver-brain axis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Obesity and overweight are major global public health challenges with complex origins. Their profound impact on metabolic health, including an increased risk of type 2 diabetes and cardiovascular diseases, arises from dysregulated metabolic processes like insulin resistance and inflammation. Adipose tissue, acting as an endocrine organ, secretes molecules that influence systemic metabolic homeostasis. Understanding these mechanisms is crucial for developing effective prevention and treatment strategies against obesity-related complications.
The central nervous system (CNS) plays a critical role in the development of obesity by regulating appetite, energy expenditure, and metabolic balance. Brain regions such as the hypothalamus and brainstem control feeding behavior, responding to hunger and satiety signals. The dysregulation of these pathways, influenced by genetics and environment, can increase food intake. Additionally, the CNS integrates signals from peripheral organs, contributing to metabolic dysfunction. Understanding these intricate brain–body interactions is vital for addressing obesity effectively.
This Special Issue aims to compile the most recent and cutting-edge data on the molecular and cellular adaptations that contribute to obesity and its metabolic consequences. We particularly welcome submissions that shed light on novel therapeutic targets or interventions with the potential to improve metabolic health.
We welcome the submission of original research articles and reviews focusing on, but not limited to, the following topics:
- Neuro-immune metabolism;
- CNS-peripheral organ communication;
- Adipose tissue inflammation;
- Gut microbiota and obesity;
- Epigenetic regulation in obesity;
- Neuroendocrine control of metabolism;
- Pharmacological interventions for obesity;
- Protective effects of bioactive compounds and dietary components.
Dr. Natalia Ferreira Mendes
Dr. Eliana Pereira De Araújo
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- glial cells
- blood–brain barrier
- gut microbiota
- immune surveillance
- glucose metabolism
- energy me-tabolism
- food intake
- brown adipose tissue
- leptin
- insulin resistance
- bioactive compounds
- epige-netics
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