Novel and Emerging Biomarkers in Neurodegenerative Disorders
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".
Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 561
Special Issue Editors
Interests: dementia; stroke; Alzheimer’s disease; blood–brain barrier; cerebrovasculature; perivascular spaces; magnetic resonance imaging
Special Issues, Collections and Topics in MDPI journals
Interests: neuropharmacology; psychoneuroimmunoendocrinology; environmental neuroscience; glial cells; metabolomic
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the last decade, advancements in neuroimaging and omics fields, including metabolomics, genomics, transcriptomics, proteomics, lipidomics and radiomics, have made it possible to significantly enhance our knowledge regarding the biological mechanisms that underlie healthy aging and neurodegenerative diseases such as Alzheimer’s disease, Parkinsons’s disease, and multiple sclerosis. In particular, the integration of multiple omics approaches with biofluid- and imaging-based biomarkers enables insights to be gained into the metabolic processes characterizing specific stages of the investigated diseases, and how they are affected by certain treatments. From a clinical perspective, this knowledge is particularly crucial not only for the development of strategies for the treatment and prevention of these pathologies, but also for the optimization of the current diagnostic frameworks and clinical management of patients.
This Special Issue aims to include preclinical, population-based, and clinical studies that investigate the biological processes underlying neurodegenerative diseases in order to identify novel biomarkers. Investigations integrating various technologies with one or more omics approaches are particularly encouraged. Methodological articles presenting novel strategies for biomarker discovery and validation are also highly welcome.
Dr. Giuseppe Barisano
Dr. Silvia Alboni
Guest Editors
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Keywords
- neurodegenerative diseases
- Alzheimer’s disease
- Parkinson’s disease
- Multiple Sclerosis
- Huntington’s disease
- small vessel disease
- vascular cognitive impairment and dementia
- dementia
- neuroimaging
- biofluid
- plasma
- cerebrospinal fluid
- metabolomics
- proteomics
- lipidomics
- transcriptomics
- genomics
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