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Micromachines
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Organic Bioelectronics for Bioengineering Application
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Organic Bioelectronics for Bioengineering Application

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".

Deadline for manuscript submissions: closed (28 February 2023) | Viewed by 5210

Special Issue Editors

Dr. Keying Guo

E-Mail Website
Guest Editor
Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955, Saudi Arabia
Interests: biosensor and bioelectronics; point-of-care diagnostics; porous silicon
Dr. Anil Köklü

E-Mail Website
Guest Editor
Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955, Saudi Arabia
Interests: bioelectronics; micro/nanofluidics; lab-on-a-chip; electrokinetics
Dr. Cheng Jiang

E-Mail Website
Guest Editor
The School of Medicine, Life and Health Sciences (MED|LHS), The Chinese University of Hong Kong, Shenzhen, Shenzhen 518172, China
Interests: biosensing device; biomarker discovery pipeline; extracellular vesicles; neurodegenerative disease; liquid biopsy

Special Issue Information

Dear Colleagues,

Organic bioelectronics-enabled smart devices have shown their potential to tackle critical challenges in bioengineering applications associated with disease diagnostics, food safety, agriculture, and environmental monitoring. This Special Issue aims to introduce cutting-edge research activities in organic bioelectronics, revealing the open challenges for building next-generation bioelectronic devices. The Special Issue welcomes original and review articles, which will present current high-impact research topics as well as future perspectives in bioelectronics.

Key topics include, but are not limited to, the following: 1) organic bioelectronic device and system design, 2) smart biosensors and bioelectronic systems, 3) wearable and implantable bioelectronics, 4) self-powered and integrated bioelectronics, 5) lab-on-a-chip microsystems, 6) biomedical signal processing of bioelectronics, 7) in vitro or in vivo monitoring systems for biological signals, and 8) machine learning for smart bioelectronics.

We look forward to receiving your submissions!

Dr. Keying Guo
Dr. Anil Köklü
Dr. Cheng Jiang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biosensors
  • organic bioelectronics
  • wearable and implantable bioelectronics
  • biomarker detection
  • nanostructured biosensors
  • smart bioelectronics
  • lab-on-a-chip

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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12 pages, 9745 KiB  
Article
Unraveling an Ultrafast Electron Transport Mechanism in a Photocatalytic “Micromachine” for Their Potential Light Harvesting Applications
by Nivedita Pan, Lopamudra Roy, Md. Nur Hasan, Amrita Banerjee, Ria Ghosh, Meshari A. Alsharif, Basim H. Asghar, Rami J. Obaid, Arpita Chattopadhyay, Ranjan Das, Saleh A. Ahmed and Samir Kumar Pal
Micromachines 2023, 14(5), 980; https://doi.org/10.3390/mi14050980 - 29 Apr 2023
Cited by 2 | Viewed by 1696
Abstract
Following the seminal discovery of Richard Feynman, several micromachines have been made that are capable of several applications, such as solar energy harvesting, remediation of environmental pollution, etc. Here we have synthesized a nanohybrid combining TiO2 nanoparticle and light harvesting robust organic [...] Read more.
Following the seminal discovery of Richard Feynman, several micromachines have been made that are capable of several applications, such as solar energy harvesting, remediation of environmental pollution, etc. Here we have synthesized a nanohybrid combining TiO2 nanoparticle and light harvesting robust organic molecule RK1 (2-cyano-3-(4-(7-(5-(4-(diphenylamino)phenyl)-4-octylthiophen-2-yl)benzo[c][1,2,5] thiadiazol-4-yl)phenyl) acrylic acid) as a model micromachine having solar light harvesting ability potential for application in photocatalysis, preparation of solar active devices, etc. Detailed structural characterization, including High Resolution Transmission Electronic Microscopy (HRTEM) and Fourier-transform infrared spectroscopy (FTIR), has been performed on the nanohybrid. We have studied the excited-state ultrafast dynamics of the efficient push-pull dye RK1 in solution, on mesoporous semiconductor nanoparticles, and in insulator nanoparticles by streak camera (resolution of the order of 500 fs). The dynamics of such photosensitizers in polar solvents have been reported, and it has been observed that completely different dynamics occur when they are attached to the surface of the semiconductor/insulator nanosurface. A femtosecond-resolved fast electron transfer has been reported when photosensitizer RK1 has been attached to the surface of the semiconductor nanoparticle, which in turn plays a crucial role in the development of an efficient light harvesting material. The generation of reactive oxygen species as a result of femtosecond-resolved photoinduced electron injection in the aqueous medium is also investigated in order to explore the possibility of redox-active micromachines, which are found to be crucial for efficient and enhanced photocatalysis. Full article
(This article belongs to the Special Issue Organic Bioelectronics for Bioengineering Application)
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13 pages, 18586 KiB  
Article
Reduction of Viral and Bacterial Activity by Using a Self-Powered Variable-Frequency Electrical Stimulation Device
by Hsin-Yi Tsai, Yu-Hsuan Lin, Kuo-Cheng Huang, Ching-Ching Yang, Chun-Han Chou and Liang-Chieh Chao
Micromachines 2023, 14(2), 282; https://doi.org/10.3390/mi14020282 - 21 Jan 2023
Cited by 2 | Viewed by 2952
Abstract
Viruses and bacteria, which can rapidly spread through droplets and saliva, can have serious effects on people’s health. Viral activity is traditionally inhibited using chemical substances, such as alcohol or bleach, or physical methods, such as thermal energy or ultraviolet-light irradiation. However, such [...] Read more.
Viruses and bacteria, which can rapidly spread through droplets and saliva, can have serious effects on people’s health. Viral activity is traditionally inhibited using chemical substances, such as alcohol or bleach, or physical methods, such as thermal energy or ultraviolet-light irradiation. However, such methods cannot be used in many applications because they have certain disadvantages, such as causing eye or skin injuries. Therefore, in the present study, the electrical stimulation method is used to stimulate a virus, namely, coronavirus 229E, and two types of bacteria, namely, Escherichia coli and Staphylococcus aureus, to efficiently reduce their infectivity of healthy cells (such as the Vero E6 cell in a viral activity-inhibition experiment). The infectivity effects of the aforementioned virus and bacteria were examined under varying values of different electrical stimulation parameters, such as the stimulation current, frequency, and total stimulation time. The experimental results indicate that the activity of coronavirus 229E is considerably inhibited through direct-current pulse stimulation with a current of 25 mA and a frequency of 2 or 20 Hz. In addition, E. coli activity was reduced by nearly 80% in 10 s through alternating-current pulse stimulation with a current of 50 mA and a frequency of 25 Hz. Moreover, a self-powered electrical stimulation device was constructed in this study. This device consists of a solar panel and battery to generate small currents with variable frequencies, which has advantages of self-powered and variable frequencies, and the device can be utilized on desks, chairs, or elevator buttons for the inhibition of viral and bacterial activities. Full article
(This article belongs to the Special Issue Organic Bioelectronics for Bioengineering Application)
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