Microsystems for Cancer Therapeutic Approach
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B：Biology and Biomedicine".
Deadline for manuscript submissions: closed (1 March 2021) | Viewed by 5313
Special Issue Editors
2. LIMMS/CNRS-IIS, Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan
Interests: BioMEMS and cancer; microsystems technologies; actuators and sensors; biomedical micro devices; biomechanical and bioelectrical cell measurements; simulation and analysis
Special Issue Information
Dear Colleagues,
According to the World Health Organization, cancer, responsible for an estimated 9.4 million deaths per year, is the second leading cause of death globally. Despite intensive research programs, while many other major killers like heart disease and pneumonia have shown dramatic improvements and spectacular advances in treatment, the mortality and morbidity rates for most cancers have remained almost unchanged.
Cancer arises from the cellular transformation into tumour cells in a multistage process that generally progresses from a pre-cancerous lesion to a malignant tumour. These changes are the result of the interaction between a person's genetic factors and intricate multiscale molecular and cellular mechanisms triggered in cell environment, tissues and organs.
The development of smart microdevices (lab on chip, bioMEMS, and microfluidics) allowed for the study of cancer biology at the proper scale to characterise cancer cells, analyse metastatic mechanisms and mimic tumour microenvironment, among others. Nevertheless, as mentioned, the research priority has to be set far beyond microtechnologies, approaching the translational level to allow exchanges between fundamental research and clinics.
This Special Issue on Microsystems for Cancer Therapeutic Approach invites manuscripts on research aiming to develop clinically-oriented experiments and assays in microdevices. Papers involving cancer surgery (e.g., margin detection, and neo-tissues), chemotherapy (e.g., drug development on realistic in vitro models), immunotherapy (e.g., high-throughput cellular interaction screening), and radiotherapy (e.g., enhanced radiative effect and selectivity) are encouraged to emphasize the translational nature of the research on cancer diagnostics, treatment, care, and monitoring. The project design with clinicians, the evaluation of the translational opportunity and the planned route toward the preclinical assays are also welcome to be discussed in the manuscripts.
Prof. Dr. Dominique Collard
Prof. Dr. Cagatay Tarhan
Guest Editors
Manuscript Submission Information
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Keywords
- Microsystems for Biology and Life Science (BioMEMS)
- Lab on Chip
- Cancer
- Therapeutic Approach
- Cancer Surgery
- Chemotherapy
- Cancer Immunotherapy
- Radiotherapy
- Tumour on Chip
- Tumour Microenvironment
- Inflammation and Cancer
- Blood Vessel/Tumour Interactions
- Tumosphere
- Cell Analysis
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