Point-of-Care Devices for Pathogen Detection

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B4: Point-of-Care Devices".

Deadline for manuscript submissions: closed (10 December 2022) | Viewed by 5136

Special Issue Editor


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Guest Editor
Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, California Northstate University, Elk Grove, CA 95757, USA
Interests: point of care diagnostics; lab-on-a-chip; microfluidics; organs-on-chip
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Special Issue Information

Dear Colleagues,

Progressing point-of-care devices for early diagnosis of infectious diseases has great substantial merit worldwide, especially in remote regions where healthcare and medical services are limited. Point-of-care diagnostic devices are rapidly increasing in demand, and the global market is estimated to reach approximately 43 billion by 2026.

This Special Issue focuses on rapid detection methods for infectious diseases using microfluidics and lab-on-a-chip technologies as toolsets to explore the possibility of realizing and commercializing point-of-care diagnostic devices. The development of science in the last three decades, especially in micro- and nanotechnology, materials sciences and biotechnology, has opened a great opportunity for the rapid, cost-efficient detection of ultra-low concentrations and volumes of reagents, giving rise to applications and implementation in the detection of a broad spectrum of pathogens by utilizing different biomarkers, e.g., DNA, mRNA, proteins and antibodies.

As the Guest Editor of this Special Issue, I would like to thank the contributors in advance for their valuable time and for submitting papers of a high quality. If you have any research in this field that you would like to publish, you are welcome to submit your work to this Special Issue.

Dr. Trieu Nguyen
Guest Editor

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Keywords

  • point-of-care devices
  • pathogen detection
  • diagnostics
  • DNA
  • microfluidics
  • antibody
  • protein
  • PCR
  • LAMP
  • fluorescence
  • phosphorescence

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Published Papers (1 paper)

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Review

20 pages, 3390 KiB  
Review
Microfluidics-Based POCT for SARS-CoV-2 Diagnostics
by Binfeng Yin, Xinhua Wan, A. S. M. Muhtasim Fuad Sohan and Xiaodong Lin
Micromachines 2022, 13(8), 1238; https://doi.org/10.3390/mi13081238 - 1 Aug 2022
Cited by 26 | Viewed by 4678
Abstract
A microfluidic chip is a tiny reactor that can confine and flow a specific amount of fluid into channels of tens to thousands of microns as needed and can precisely control fluid flow, pressure, temperature, etc. Point-of-care testing (POCT) requires small equipment, has [...] Read more.
A microfluidic chip is a tiny reactor that can confine and flow a specific amount of fluid into channels of tens to thousands of microns as needed and can precisely control fluid flow, pressure, temperature, etc. Point-of-care testing (POCT) requires small equipment, has short testing cycles, and controls the process, allowing single or multiple laboratory facilities to simultaneously analyze biological samples and diagnose infectious diseases. In general, rapid detection and stage assessment of viral epidemics are essential to overcome pandemic situations and diagnose promptly. Therefore, combining microfluidic devices with POCT improves detection efficiency and convenience for viral disease SARS-CoV-2. At the same time, the POCT of microfluidic chips increases user accessibility, improves accuracy and sensitivity, shortens detection time, etc., which are beneficial in detecting SARS-CoV-2. This review shares recent advances in POCT-based testing for COVID-19 and how it is better suited to help diagnose in response to the ongoing pandemic. Full article
(This article belongs to the Special Issue Point-of-Care Devices for Pathogen Detection)
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